6-(p-Toluidino)-2-naphthalenesulfonic acid sodium salt
6-(p-Toluidino)-2-naphthalenesulfonic acid sodium salt (CAS 53313-85-2) is a sodium salt derived from naphthalene. This compound serves as a fluorescent probe, primarily utilized to assess the conformational state of proteins. With a molecular weight of 335.35 g/mol, it is a valuable reagent in biochemical research and analytical spectroscopy for monitoring protein structure and dynamics.
- IUPAC
- Sodium 6-(p-toluidino)-2-naphthalenesulfonate,TNS
- Synonyms
- Sodium 6-(p-toluidino)-2-naphthalenesulfonateTNS

Protein Conformation Studies
This compound functions as a fluorescent probe to investigate the conformational state of proteins. Its fluorescence properties change in response to alterations in the protein's structure.
Spectroscopic pH Indicator
As a pH-sensitive probe, it can be employed in spectroscopic methods for monitoring pH changes within a specific range. This is valuable for biochemical assays and cell studies.
Fluorescent Labeling
The molecule can be used as a fluorescent label in various biological and chemical applications where a fluorescent tag is required for detection or tracking.
| Molecular weight | 335.35 |
|---|---|
| Empirical formula | C17H14NNaO3S |
| Storage temperature | 2-8°C |
| Application | Fluorescent probe for the conformational state of proteins. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(p-Toluidino)-2-naphthalenesulfonic acid sodium salt primarily used for?
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It is principally used as a fluorescent probe to determine the conformational state of proteins and as a pH-sensitive indicator in spectroscopic analyses.
What are the CAS number and empirical formula for this compound?
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The CAS number is 53313-85-2, and the empirical formula is C17H14NNaO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. The specific grade and purity are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
What are the safety and handling recommendations?
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This compound is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is recommended to use a dust mask (N95 type), eyeshields, and gloves. Ensure good ventilation.
How is this chemical packed and shipped by TSS?
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Tech Serve Solutions, a global supplier and exporter, ensures appropriate packaging and shipping procedures adhering to international regulations for fine chemicals.
How can I request a sample or quote for 6-(p-Toluidino)-2-naphthalenesulfonic acid sodium salt?
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Please contact our sales team directly via the website or provide your requirements through the 'Request a Quote' or 'Request a Sample' forms.
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