3-(tert-Butyldimethylsilyloxy)phenylboronic acid
3-(tert-Butyldimethylsilyloxy)phenylboronic acid (CAS: 261621-12-9), with the molecular formula C 6 H 4 OSi(CH 3 )2C(CH 3 )3B(OH) 2 , is a versatile organoboron compound. It serves as a key building block in organic synthesis, particularly in cross-coupling reactions. Its structure, featuring a protected hydroxyl group, allows for selective functionalization in complex molecule construction.
Suzuki-Miyaura Coupling Reagent
This aryl boronic acid is a valuable substrate in Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of carbon-carbon bonds by reacting with organic halides or pseudohalides in the presence of a palladium catalyst.
Organic Synthesis Intermediate
The compound acts as an important intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. The tert-butyldimethylsilyl (TBS) protecting group enables controlled sequential reactions.
Research and Development
Used in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities. Its specific structure allows for targeted modifications in medicinal chemistry programs.
| Molecular weight | 252.19 |
|---|---|
| Linear formula | C6H4OSi(CH3)2C(CH3)3B(OH)2 |
| Grade | technical grade |
| Melting point | 86-91 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(tert-Butyldimethylsilyloxy)phenylboronic acid used for?
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3-(tert-Butyldimethylsilyloxy)phenylboronic acid is primarily used as a reagent and intermediate in organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions for C-C bond formation, and in the development of pharmaceuticals and advanced materials.
What are the CAS number and chemical formula for 3-(tert-Butyldimethylsilyloxy)phenylboronic acid?
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The CAS number is 261621-12-9, and the chemical formula is C 6 H 4 OSi(CH 3 )2C(CH 3 )3B(OH) 2 .
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a technical grade material. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 3-(tert-Butyldimethylsilyloxy)phenylboronic acid be handled?
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This compound requires careful handling. Use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for comprehensive guidance.
Is this product exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-(tert-Butyldimethylsilyloxy)phenylboronic acid.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number.
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