3-(tert-Butyldimethylsilyloxy)glutaric anhydride
3-(tert-Butyldimethylsilyloxy)glutaric anhydride (CAS 91424-40-7), with the molecular formula C11H20O4Si and a molecular weight of 244.36 g/mol, is a valuable organic building block. This carboxylic acid anhydride derivative is primarily utilised in organic synthesis, offering a protected form of glutaric acid for complex molecular construction. Its specific silyloxy protection allows for selective reactions, making it a useful intermediate in the development of novel compounds.

Organic Synthesis Intermediate
Serves as a protected difunctional building block in multi-step organic synthesis pathways. The tert-butyldimethylsilyl (TBDMS) ether provides protection to one of the hydroxyl groups, enabling selective manipulation of the anhydride functionality.
Pharmaceutical Research
Aids in the synthesis of complex organic molecules that may serve as potential pharmaceutical candidates. Its structure allows for the introduction of a glutaric acid moiety into larger molecular frameworks.
Material Science
Can be employed in the development of novel polymers or functional materials where its anhydride or protected hydroxyl group can be incorporated into a polymer backbone or side chain.
| Molecular weight | 244.36 |
|---|---|
| Empirical formula | C11H20O4Si |
| Assay | 99% |
| Storage temperature | 2-8°C |
| Melting point | 79-81 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(tert-Butyldimethylsilyloxy)glutaric anhydride used for?
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3-(tert-Butyldimethylsilyloxy)glutaric anhydride is primarily used as a building block in organic synthesis, particularly in the pharmaceutical and material science sectors for constructing complex molecules.
What are the CAS number and formula for 3-(tert-Butyldimethylsilyloxy)glutaric anhydride?
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The CAS number is 91424-40-7 and the molecular formula is C11H20O4Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(tert-Butyldimethylsilyloxy)glutaric anhydride with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 3-(tert-Butyldimethylsilyloxy)glutaric anhydride be handled safely?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, and ensure adequate ventilation.
Is 3-(tert-Butyldimethylsilyloxy)glutaric anhydride a controlled substance?
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The provided data does not indicate that 3-(tert-Butyldimethylsilyloxy)glutaric anhydride is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details are confirmed upon order.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly via our website or sales representatives to request a quote or sample of 3-(tert-Butyldimethylsilyloxy)glutaric anhydride.
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