6-Azauracil
6-Azauracil (CAS 461-89-2), with the molecular formula C3H3N3O2 and a molecular weight of 113.07, is a heterocyclic compound primarily employed as a growth inhibitor. It functions by depleting intracellular GTP and UTP nucleotide pools, thereby affecting various microorganisms. This biochemical is a valuable reagent in research settings for studies involving nucleotide metabolism and microbial growth control.
- IUPAC
- 1,2,4-Triazine-3,5(2H,4H)-dione,3,5-Dihydroxy-1,2,4-triazine,6-Aza-2,4-dihydroxypyrimidine,6-AU
- Synonyms
- 1,2,4-Triazine-3,5(2H,4H)-dione3,5-Dihydroxy-1,2,4-triazine6-Aza-2,4-dihydroxypyrimidine6-AU
Microbial Growth Inhibition
6-Azauracil serves as a potent growth inhibitor for various microorganisms. Its mechanism involves the depletion of essential intracellular nucleotide pools, specifically GTP and UTP.
Biochemical Research
Utilised as a biochemical reagent in laboratory settings, 6-Azauracil aids in studying nucleotide metabolism and its impact on cellular processes. It is particularly useful for investigating pathways related to pyrimidine and purine biosynthesis.
Nucleotide Pool Depletion Studies
This compound is instrumental in experimental research designed to understand the critical roles of GTP and UTP. By selectively depleting these pools, researchers can elucidate their functions in microbial systems.
| Molecular weight | 113.07 |
|---|---|
| Empirical formula | C3H3N3O2 |
| Assay | ≥98% |
| Application | 6-Azauracil (6-AU) is used as a growth inhibitor of various microorganisms via depletion of intracellular GTP and UTP nucleotide pools. |
| Melting point | 274-275 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Azauracil used for?
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6-Azauracil is used as a growth inhibitor of various microorganisms by depleting intracellular GTP and UTP nucleotide pools. It is also used in biochemical research.
What is the CAS number and formula for 6-Azauracil?
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The CAS number for 6-Azauracil is 461-89-2, and its empirical formula is C3H3N3O2.
What grade and purity does Tech Serve Solutions supply for 6-Azauracil?
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Tech Serve Solutions supplies 6-Azauracil with a minimum assay of ≥98%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should 6-Azauracil be handled safely?
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Handle 6-Azauracil with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.
How is 6-Azauracil packed, shipped, and exported?
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6-Azauracil is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions. Specific packaging details depend on order quantity and destination.
How can I request a quote or sample of 6-Azauracil?
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To request a quote or sample of 6-Azauracil, please contact our sales team through the website or provide your requirements via email.
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