6-Azauridine

CAS 54-25-1C8H11N3O6Biochemicals & Reagents

6-Azauridine (CAS 54-25-1), with the molecular formula C8H11N3O6 and a molecular weight of 245.19 g/mol, is a nucleoside analog. It functions by inhibiting the conversion of orotic acid to UMP, a key step in pyrimidine biosynthesis. This mechanism makes it a valuable tool in biochemical research, particularly in studies related to antiviral mechanisms and cellular metabolism.

IUPAC: 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione,6-Azauracil riboside
Synonyms: 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione6-Azauracil riboside

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6-Azauridine (C8H11N3O6) — chemical structure, CAS 54-25-1; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsNucleoside AnalogsNucleosidesNucleotidesOligonucleotides

01 /Applications

Antiviral Studies

6-Azauridine is utilised in research settings to investigate antiviral mechanisms. Its ability to interfere with nucleotide synthesis pathways makes it a compound of interest for understanding how viruses replicate and how their processes can be disrupted.

Biochemical Research

As a nucleoside analog, 6-Azauridine serves as a probe in fundamental biochemical research. It aids in elucidating metabolic pathways, particularly those involving pyrimidine synthesis, and its effects on cellular processes.

Enzyme Inhibition Studies

This compound is employed to study enzymes involved in nucleotide metabolism. Specifically, it targets enzymes that process orotic acid, providing insights into enzyme kinetics and inhibition mechanisms.

02 /Properties

Molecular weight	245.19
Empirical formula	C8H11N3O6
Storage temperature	2-8°C
Application	6-Azauridine (AzUrd) blocks the conversion of orotic acid into UMP and it is used in antiviral studies.
Melting point	157-159 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	20/21/22-40
Safety statements (S)	22-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

54-25-1

MDL number

MFCD00006472

PubChem substance

24890597

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 6-Azauridine used for?

6-Azauridine is used in biochemical research, particularly in antiviral studies, and to investigate its role in blocking the conversion of orotic acid to UMP.

What is the CAS number and molecular formula for 6-Azauridine?

The CAS number for 6-Azauridine is 54-25-1, and its molecular formula is C8H11N3O6.

What grade and purity does Tech Serve Solutions supply for 6-Azauridine?

Tech Serve Solutions supplies 6-Azauridine as a research-grade chemical. We do not claim it to be of USP, BP, or EP grade.

How should 6-Azauridine be handled safely?

Handle 6-Azauridine with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid dust formation and inhalation. It carries hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H332 (Harmful if inhaled), and H351 (Suspected of causing cancer).