5-(N,N-Hexamethylene)amiloride
5-(N,N-Hexamethylene)amiloride (CAS: 1428-95-1) is a notable derivative of amiloride, with a molecular weight of 311.77 g/mol. This compound is recognised for its activity as a modulator of ion channels, particularly sodium channels. Its primary applications lie in biochemical research, focusing on cell physiology and signaling pathways. Available from Tech Serve Solutions, it serves as a critical reagent for scientific investigation into ion transport mechanisms.
- IUPAC
- HMA
- Synonyms
- HMA5-(Hexamethylene)amiloride
Ion Channel Research
5-(N,N-Hexamethylene)amiloride is utilised as a research tool to investigate the function and modulation of various ion channels, including epithelial sodium channels (ENaC). It aids in understanding the physiological roles of these channels in cellular processes.
Cellular Physiology Studies
This compound aids in the study of cellular ion homeostasis and transport. Researchers employ it to explore how altering ion flux impacts cell behaviour and function in different biological systems.
Neuroscience Research
As a modulator of voltage-gated ion channels and sodium channel modulators, it finds application in neuroscience research for investigating neuronal excitability and signaling.
| Molecular weight | 311.77 |
|---|---|
| Empirical formula | C12H18ClN7O |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(N,N-Hexamethylene)amiloride used for?
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5-(N,N-Hexamethylene)amiloride is primarily used in research for studying ion channels, particularly sodium channels, and investigating cellular physiology and signaling pathways. It is a valuable tool in neuroscience and cell biology research.
What is the CAS number and formula for 5-(N,N-Hexamethylene)amiloride?
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The CAS number for 5-(N,N-Hexamethylene)amiloride is 1428-95-1. Its empirical formula is C12H18ClN7O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-(N,N-Hexamethylene)amiloride as a research-grade chemical. The specific purity is not detailed in the provided data; TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this compound?
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5-(N,N-Hexamethylene)amiloride is classified as toxic (GHS06, Danger). Hazards include acute toxicity if swallowed, in contact with skin, or if inhaled (H301-H311-H331). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, must be used. Handle only in well-ventilated areas.
How is this chemical packed, shipped, and exported?
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This chemical is typically stored at 2-8°C. Shipping and export procedures follow all relevant international regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a sample or a quote for 5-(N,N-Hexamethylene)amiloride?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or direct inquiry channels. Provide the product name and CAS number for prompt service.
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