5-Bromo-2-(difluoromethyl)pyridine
5-Bromo-2-(difluoromethyl)pyridine (CAS: 845827-13-6), a halogenated pyridine derivative with the molecular formula C6H4BrF2N and a molecular weight of 208.00 g/mol, serves as a valuable building block in organic synthesis. Its structure, featuring both a bromine atom and a difluoromethyl group on the pyridine ring, allows for diverse chemical transformations. This compound is primarily utilised in the development of novel pharmaceutical intermediates and advanced materials, owing to its reactivity and the unique properties it can impart to target molecules.
- IUPAC
- 3-Bromo-6-(difluoromethyl)pyridine
Pharmaceutical Intermediate Synthesis
This pyridine derivative is employed in multi-step syntheses for the creation of new active pharmaceutical ingredients (APIs). The bromine and difluoromethyl functionalities offer strategic points for molecular elaboration and property tuning in drug discovery programmes.
Agrochemical Development
The unique combination of a halogen and a difluoromethyl group on a heterocyclic scaffold makes it a useful intermediate for designing novel agrochemical compounds with potential herbicidal or insecticidal activity.
Materials Science Research
It can be incorporated into the synthesis of advanced materials, where the fluorinated pyridine motif may contribute to specific electronic or physical properties in polymers or organic electronic devices.
Organic Synthesis Reagent
As a functionalised heterocyclic building block, it facilitates the construction of complex organic molecules through various coupling and substitution reactions, supporting academic and industrial research.
| Molecular weight | 208.00 |
|---|---|
| Empirical formula | C6H4BrF2N |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 35-40 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 89 °C / 192.2 °F |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-(difluoromethyl)pyridine used for?
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5-Bromo-2-(difluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical intermediates, agrochemicals, and advanced materials.
What is the CAS number and formula for 5-Bromo-2-(difluoromethyl)pyridine?
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The CAS number is 845827-13-6 and the empirical formula is C6H4BrF2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Bromo-2-(difluoromethyl)pyridine with a minimum assay of 95%. This product is supplied for research and development purposes and TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 5-Bromo-2-(difluoromethyl)pyridine be handled and stored?
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This compound is classified as Danger, with hazards including toxicity if swallowed and skin/eye/respiratory irritation (H301-H315-H319-H335). It should be handled with appropriate personal protective equipment in a well-ventilated area. Storage is recommended at 2-8°C.
Is 5-Bromo-2-(difluoromethyl)pyridine a controlled substance?
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Based on the provided safety data, there is no indication that 5-Bromo-2-(difluoromethyl)pyridine is a scheduled or controlled substance.
How is this chemical packed and shipped?
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5-Bromo-2-(difluoromethyl)pyridine is shipped according to UN 2811 6.1 / PGIII regulations for toxic solids. Packaging details can be confirmed upon request, and TSS is experienced in global export.
How can I request a sample or quote for 5-Bromo-2-(difluoromethyl)pyridine?
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To request a sample or a quotation, please contact our sales team via the website or provide your details through the product inquiry form. Our team will respond promptly to your request.
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