5-Bromo-2-(dimethylamino)pyrimidine
5-Bromo-2-(dimethylamino)pyrimidine (CAS: 38696-21-8, C6H8BrN3, MW: 202.05) is a halogenated heterocyclic building block. This compound serves as a valuable intermediate in chemical synthesis, particularly within pharmaceutical research and development. Its structure, featuring a pyrimidine core with a bromine atom and a dimethylamino group, allows for diverse chemical transformations, making it a versatile reagent for creating more complex organic molecules.
- IUPAC
- 2-(Dimethylamino)-5-bromopyrimidine,5-Bromo-N,N-dimethylpyrimidin-2-amine
- Synonyms
- 2-(Dimethylamino)-5-bromopyrimidine5-Bromo-N,N-dimethylpyrimidin-2-amine

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs). The pyrimidine ring is a common scaffold in many drug molecules, and the bromine atom provides a handle for further functionalisation.
Organic Synthesis Reagent
Acts as a key building block for constructing complex organic structures. Its reactivity can be exploited in various coupling reactions and derivatisations to create novel compounds.
Research and Development
Employed in academic and industrial research laboratories for exploring new chemical entities and synthetic pathways. It contributes to the discovery of new materials and therapeutic agents.
| Molecular weight | 202.05 |
|---|---|
| Empirical formula | C6H8BrN3 |
| Assay | 97% |
| Melting point | 74-81 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-(dimethylamino)pyrimidine used for?
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5-Bromo-2-(dimethylamino)pyrimidine is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceutical research and development. It is instrumental in creating complex heterocyclic compounds.
What are the CAS number and formula for 5-Bromo-2-(dimethylamino)pyrimidine?
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The CAS number is 38696-21-8, and the empirical formula is C6H8BrN3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Bromo-2-(dimethylamino)pyrimidine with an assay of 97%. TSS does not represent this product as USP/BP/EP or any other pharmacopoeia grade.
How should 5-Bromo-2-(dimethylamino)pyrimidine be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as harmful if swallowed and causes skin and eye irritation.
Is 5-Bromo-2-(dimethylamino)pyrimidine a controlled substance?
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The provided data does not indicate that 5-Bromo-2-(dimethylamino)pyrimidine is a controlled substance.
How is 5-Bromo-2-(dimethylamino)pyrimidine packed and shipped?
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5-Bromo-2-(dimethylamino)pyrimidine is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for 5-Bromo-2-(dimethylamino)pyrimidine?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or by direct inquiry, providing your contact details and required quantity.
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