4-(Trifluoromethylthio)aniline
4-(Trifluoromethylthio)aniline (CAS 372-16-7, CF3SC6H4NH2) is a chemical building block with a molecular weight of 193.19 g/mol. It is primarily used in organic synthesis for the introduction of the trifluoromethylthio group. Its characteristics make it a valuable intermediate in the development of novel compounds within research and development settings, particularly for agrochemical and pharmaceutical applications. This compound is supplied with a minimum purity of 97%.

Organic Synthesis Intermediate
Utilised as a key building block in the construction of more complex organic molecules. Its unique trifluoromethylthio functional group allows for specific chemical transformations.
Pharmaceutical Research
A valuable reagent in medicinal chemistry for the synthesis of potential drug candidates. The trifluoromethylthio moiety can influence lipophilicity and metabolic stability.
Agrochemical Development
Employed in the research and development of new pesticides and herbicides. The incorporation of the CF3S group can impart desirable biological activity.
| Molecular weight | 193.19 |
|---|---|
| Linear formula | CF3SC6H4NH2 |
| Assay | 97% |
| Boiling point | 102-103 °C/8 mmHg(lit.) |
| Density | 1.351 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.528(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(Trifluoromethylthio)aniline used for?
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4-(Trifluoromethylthio)aniline is primarily used as a building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries for developing new compounds.
What is the CAS number and chemical formula for 4-(Trifluoromethylthio)aniline?
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The CAS number is 372-16-7 and the chemical formula is CF3SC6H4NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(Trifluoromethylthio)aniline with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 4-(Trifluoromethylthio)aniline be handled?
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Handling requires caution due to hazards including harmful effects if swallowed, in contact with skin, or if inhaled (H302, H312, H332). Use appropriate personal protective equipment such as eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation.
Is 4-(Trifluoromethylthio)aniline available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals like 4-(Trifluoromethylthio)aniline, adhering to all relevant shipping regulations.
How can I request a sample or quote for 4-(Trifluoromethylthio)aniline?
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Please contact our sales team through the website or by phone to request a sample or a formal quotation for 4-(Trifluoromethylthio)aniline.
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