4-(N-Phthalimidinyl)benzenesulfonyl chloride
4-(N-Phthalimidinyl)benzenesulfonyl chloride (CAS: 114341-14-9) is a chemical compound with the molecular formula C14H10ClNO3S and a molecular weight of 307.75 g/mol. Supplied by Tech Serve Solutions, this compound is primarily used as a derivatization reagent, particularly for fluorescence detection in analytical and chromatographic applications. Its specific chemical properties make it valuable in biochemical research and the development of sensitive detection methods.
- IUPAC
- (1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-4-benzenesulfonyl chloride,Phisyl chloride
- Synonyms
- Phisyl chloride

Derivatization Reagent for HPLC
This compound serves as a derivatization agent in High-Performance Liquid Chromatography (HPLC) analyses. It reacts with analytes to form fluorescent derivatives, enhancing detection sensitivity.
Fluorescence Detection
Utilised to introduce a fluorescent tag onto molecules that are otherwise non-fluorescent. The resulting derivatives can be detected at specific excitation and emission wavelengths, aiding in quantitative analysis.
Analytical Chemistry
Employed as a reagent in analytical chemistry for the sensitive determination of various compounds. Its application is particularly relevant in fields requiring high sensitivity detection, such as environmental monitoring or biochemical assays.
Biochemical Reagent
Serves as a reagent in biochemical studies. It can be used to label biomolecules for improved detection and characterisation in complex biological samples.
| Molecular weight | 307.75 |
|---|---|
| Empirical formula | C14H10ClNO3S |
| Assay | ≥98.0% (HPLC) |
| Grade | for fluorescence |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 300 nm; λem 416 nm in methanol (after derivatization with hexylamine) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(N-Phthalimidinyl)benzenesulfonyl chloride used for?
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4-(N-Phthalimidinyl)benzenesulfonyl chloride is primarily used as a derivatization reagent for fluorescence detection in analytical and chromatographic applications, including HPLC. It is also employed as a biochemical reagent.
What is the CAS number and molecular formula for 4-(N-Phthalimidinyl)benzenesulfonyl chloride?
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The CAS number is 114341-14-9, and the molecular formula is C14H10ClNO3S.
What grade and purity does Tech Serve Solutions supply for 4-(N-Phthalimidinyl)benzenesulfonyl chloride?
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Tech Serve Solutions supplies this compound with a grade specified as 'for fluorescence' and an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 4-(N-Phthalimidinyl)benzenesulfonyl chloride be handled safely?
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Based on GHS information, this compound is a warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Work in a well-ventilated area or fume hood. Avoid breathing dust.
Is 4-(N-Phthalimidinyl)benzenesulfonyl chloride suitable for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. We can provide quotations for international orders, adhering to all export regulations.
How can I request a sample or quote for 4-(N-Phthalimidinyl)benzenesulfonyl chloride?
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To request a sample or a quotation, please contact our sales department through the website or by phone. Please specify the quantity required and your shipping destination.
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