4-Acetamido-4′-isothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate
4-Acetamido-4′-isothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate (CAS 51023-76-8) is a fluorescent labeling agent with significant biochemical applications. Supplied as a hydrate with a molecular weight of 498.46 (anhydrous basis), it serves as a fluorescent marker for biological membranes. It is also known to inhibit anion permeability and inactivate Na,K-ATPase through covalent modification, acting as a potent enzyme inhibitor.
- IUPAC
- Disodium 4-acetamido-4′-isothiocyanato-stilben-2,2′-disulfonate,SITS
- Synonyms
- Disodium 4-acetamido-4′-isothiocyanato-stilben-2,2′-disulfonate, SITS
Fluorescent Membrane Labeling
This compound functions as a fluorescent marker for biological membranes, aiding in visualization and study of membrane structures and dynamics.
Enzyme Inhibition Studies
It is utilized in biochemical research to inhibit anion permeability of membranes and to inactivate Na,K-ATPase by covalently modifying a specific Lys residue.
Biochemical Research Reagent
As a biochemical reagent, it is employed in various laboratory settings for investigations into enzyme mechanisms and cellular processes.
| Molecular weight | 498.46 (anhydrous basis) |
|---|---|
| Empirical formula | C17H12N2Na2O7S3 · xH2O |
| Assay | ≥80% |
| Storage temperature | 2-8°C |
| Application | Fluorescent marker for membranes; inhibits anion permeability of membranes. Also inactivates Na,K-ATPase, by covalent modification of a specific Lys residue.1 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-42 |
| Safety statements (S) | 22-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Acetamido-4′-isothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate used for?
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This compound is primarily used as a fluorescent marker for membranes and to inhibit anion permeability. It also inactivates Na,K-ATPase by covalent modification of a specific Lys residue, acting as an enzyme inhibitor.
What are the CAS number and formula?
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The CAS number is 51023-76-8. The empirical formula is C17H12N2Na2O7S3 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥80%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this chemical?
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This compound presents hazards including being harmful if swallowed (H302), causing skin irritation (H315), eye irritation (H319), and being a respiratory sensitizer (H334) and irritant (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves, must be worn during handling. Ensure adequate ventilation and avoid dust formation.
How is this chemical packed, shipped, and exported?
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This chemical is packed in compliance with international shipping regulations. Tech Serve Solutions is an experienced global supplier and exporter, ensuring secure and compliant delivery worldwide.
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales department through the inquiry form on our website or by calling us directly.
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