4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate
4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate (CAS 67229-93-0), with the molecular formula C15H10N2OS and a molecular weight of 266.32 g/mol, is a fluorogenic derivatizing agent. This compound is primarily utilised in analytical chemistry to derivatise primary, secondary, and tertiary hydroxyl compounds and amines. Its application facilitates enhanced detection and separation in chromatographic techniques, particularly when fluorescence detection is employed.
Fluorogenic Derivatisation Agent
This isocyanate is employed to react with primary, secondary, and tertiary hydroxyl compounds and primary and secondary amines. The derivatisation process introduces a fluorophore, enhancing detection capabilities in analytical methods.
Analytical Chromatography
Following derivatisation, the resulting compounds are suitable for chromatographic separation. The fluorogenic nature of the derivatised analytes allows for sensitive detection using fluorescence detectors in techniques like HPLC.
Enhanced Detection Methods
The compound is specifically useful for applications requiring fluorescence detection due to the inherent fluorescent properties of the benzothiazole moiety in the derivatised products (λex 327 nm; λem 382 nm in methylene chloride after derivatization).
| Molecular weight | 266.32 |
|---|---|
| Empirical formula | C15H10N2OS |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Application | 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate is a fluorogenic agent use to derivatize primary, secondary and tertiary hydroxyl compounds and primary and secondary amines for analytical analysis and chromatographic separation. |
| Suitability | suitable for fluorescence |
| Melting point | 140-150 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 327 nm; λem 382 nm in methylene chloride (after derivatization with hexylamine)λex 350 nm; λem 374 nm in chlorobenzene |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate used for?
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4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate is a fluorogenic derivatizing agent used to prepare primary, secondary, and tertiary hydroxyl compounds and primary and secondary amines for analytical analysis and chromatographic separation, particularly when fluorescence detection is required.
What is the CAS number and molecular formula for 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate?
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The CAS number is 67229-93-0, and the molecular formula is C15H10N2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate with a minimum assay of 98.0% by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate be handled and stored?
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Handling requires appropriate personal protective equipment including eyeshields and gloves, and a suitable respirator filter (type N95 or P1). Store in a cool place at 2-8°C. The compound melts with decomposition around 140-150°C.
Is 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate a controlled substance?
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The provided data does not indicate that 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate is a controlled substance.
How can I request a quote or sample for this chemical?
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To request a quote or a sample of 4-(6-Methyl-2-benzothiazolyl)phenyl isocyanate, please contact the Tech Serve Solutions sales department via our website or by telephone.
How is this chemical shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, handles the packing and shipping of this chemical in compliance with all relevant regulations.
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