4-Methylumbelliferyl-β-D-glucuronide hydrate
4-Methylumbelliferyl-β-D-glucuronide hydrate (CAS: 881005-91-0; C16H16O9 · xH2O) is a high-purity (≥99.0%) fluorogenic substrate supplied by TSS. It is primarily used in biochemical research as a substrate for β-glucuronidase enzymes. The compound exhibits fluorescence upon enzymatic cleavage, making it valuable for quantitative assays in molecular biology and enzyme kinetics studies. Its reliable performance makes it a key reagent for research and development.
- IUPAC
- 4-Methylumbelliferyl-β-D-glucopyranosiduronic acid,MUG
Enzyme Assays
Serves as a fluorogenic substrate for the detection and quantification of β-glucuronidase activity. Its fluorescence allows for sensitive measurement of enzyme kinetics and reaction rates in various biological samples.
Molecular Biology Research
Utilised in molecular biology for applications such as gene expression analysis and reporter gene assays involving glucuronidase. The fluorescence generated upon cleavage is a key indicator.
Biochemical Studies
A valuable reagent for studying glycobiology and enzyme mechanisms, particularly those involving glucuronide conjugates. It aids in understanding enzyme-substrate interactions and pathways.
| Molecular weight | 352.29 (anhydrous basis) |
|---|---|
| Empirical formula | C16H16O9 · xH2O |
| Assay | ≥99.0% (HPLC) |
| Solubility | DMSO: soluble50 mg/mL, clear, colorless to very faintly yellow |
| Storage temperature | −20°C |
| Impurities tested | ≤0.1% free 4-Methylumbelliferone≤15% water |
| Suitability | suitable for fluorescence |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioXtra |
|---|---|
| Fluorescence | λex 365 nm; λem 445 nm in 0.1 M phosphate pH 6.5 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methylumbelliferyl-β-D-glucuronide hydrate used for?
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4-Methylumbelliferyl-β-D-glucuronide hydrate is primarily used as a fluorogenic substrate for the enzyme β-glucuronidase in biochemical and molecular biology research.
What is the CAS number and formula for 4-Methylumbelliferyl-β-D-glucuronide hydrate?
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The CAS number is 881005-91-0, and the empirical formula is C16H16O9 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methylumbelliferyl-β-D-glucuronide hydrate with an assay of ≥99.0% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product data.
What are the safety and handling requirements for this chemical?
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According to GHS, appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter should be used. The product has a WGK Germany rating of 3, indicating it is hazardous to water.
How is 4-Methylumbelliferyl-β-D-glucuronide hydrate packed and shipped?
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This product is typically stored at -20°C. TSS exports chemicals globally and ensures appropriate packaging for safe transport, adhering to international shipping regulations.
How can I request a quote or sample for 4-Methylumbelliferyl-β-D-glucuronide hydrate?
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Please contact our sales team directly through the TSS website or by phone to request a quotation or to arrange for a sample of 4-Methylumbelliferyl-β-D-glucuronide hydrate.
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