4′-Methoxy-3′-nitroacetophenone
4′-Methoxy-3′-nitroacetophenone (CAS 6277-38-9), with the chemical formula CH3OC6H3(NO2)C(O)CH3 and a molecular weight of 195.17 g/mol, is a valuable organic compound. It is commonly employed as a building block in chemical synthesis, particularly within organic chemistry research and development. This ketone derivative serves as a useful intermediate for creating more complex molecular structures.

Organic Synthesis Intermediate
4′-Methoxy-3′-nitroacetophenone is utilised as a key intermediate in the synthesis of various organic compounds. Its functional groups allow for diverse chemical transformations.
Research and Development
This compound finds application in academic and industrial research laboratories for the development of new chemical entities and materials.
Building Block for Complex Molecules
As a C9 building block, it provides a structured aromatic core with nitro and methoxy substituents, enabling the construction of more intricate molecular architectures.
| Molecular weight | 195.17 |
|---|---|
| Linear formula | CH3OC6H3(NO2)C(O)CH3 |
| Assay | 97% |
| Melting point | 97-100 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Methoxy-3′-nitroacetophenone used for?
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4′-Methoxy-3′-nitroacetophenone is primarily used as a building block and intermediate in organic synthesis and research and development.
What is the CAS number and chemical formula for 4′-Methoxy-3′-nitroacetophenone?
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The CAS number is 6277-38-9, and the chemical formula is CH3OC6H3(NO2)C(O)CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Methoxy-3′-nitroacetophenone with a minimum purity of 97%. This product is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for 6277-38-9?
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Handling requires personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3, indicating a hazard to water.
How is 4′-Methoxy-3′-nitroacetophenone packed and shipped?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to stringent quality and safety standards for international transport.
How can I request a quote or sample?
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To request a quote or sample of 4′-Methoxy-3′-nitroacetophenone, please contact our sales team through the website or by phone.
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