4′-Iodoacetophenone
4′-Iodoacetophenone (CAS: 13329-40-3), with the linear formula IC<sub>6</sub>H<sub>4</sub>COCH<sub>3</sub> and a molecular weight of 246.05 g/mol, is a valuable organic building block. This compound serves as a convenient substrate in palladium-catalyzed coupling reactions and is employed in the synthesis of biologically relevant molecules, such as potential anticancer agents. Supplied by Tech Serve Solutions with an assay of 98%, it is an important reagent for chemical synthesis and research.

Palladium-Catalyzed Coupling Reactions
4′-Iodoacetophenone is a useful substrate in palladium-catalyzed coupling reactions, enabling the formation of new carbon-carbon bonds in organic synthesis.
Synthesis of Quinoline Derivatives
This iodoacetophenone derivative has been utilised in the synthesis of quinoline-based compounds that are being investigated for their potential anticancer properties.
Organic Synthesis Reagent
As a functionalised aromatic ketone, it serves as a versatile building block for creating more complex organic molecules in research and development settings.
| Molecular weight | 246.05 |
|---|---|
| Linear formula | IC6H4COCH3 |
| Assay | 98% |
| Application | Convenient substrate for palladium-catalyzed coupling reactions.1 Used in the synthesis of quinoline-based potential anticancer agents.2 |
| Melting point | 82-84 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Iodoacetophenone used for?
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4′-Iodoacetophenone is used as a substrate in palladium-catalyzed coupling reactions and in the synthesis of quinoline-based potential anticancer agents. It is also a general building block for organic synthesis.
What are the CAS number and chemical formula for 4′-Iodoacetophenone?
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The CAS number for 4′-Iodoacetophenone is 13329-40-3 and its linear chemical formula is IC<sub>6</sub>H<sub>4</sub>COCH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Iodoacetophenone with a minimum purity of 98%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 4′-Iodoacetophenone be handled safely?
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4′-Iodoacetophenone is a warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation and avoid inhalation of dust.
Is 4′-Iodoacetophenone exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4′-Iodoacetophenone.
How can I request a sample or quote for 4′-Iodoacetophenone?
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To request a sample or quote, please contact the Tech Serve Solutions sales team via the website or direct inquiry channels.
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