4′-Methoxyacetophenone
4′-Methoxyacetophenone (CAS: 100-06-1) is a clear liquid or solid organic compound with the linear formula CH3OC6H4COCH3 and a molecular weight of 150.17 g/mol. This aromatic ketone is recognised for its utility as a building block in chemical synthesis. It serves as a key intermediate in the production of various fine chemicals and pharmaceuticals, owing to its reactive carbonyl group and methoxy substituent.
- IUPAC
- 4-Acetylanisole
- Synonyms
- 4-Methoxyacetophenonep-Methoxyacetophenone1-(4-methoxyphenyl)ethanoneAcetyl anisolep-Acetylanisole4-Acetyl anisoleMethyl p-methoxyphenyl ketone

Organic Synthesis Intermediate
4′-Methoxyacetophenone is widely employed as a versatile intermediate in organic synthesis. Its structure allows for various chemical transformations, making it valuable for constructing more complex molecules in academic research and industrial chemical production.
Pharmaceutical Precursor
This compound serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its characteristic functional groups can be readily modified to create diverse molecular scaffolds relevant to medicinal chemistry.
Fragrance and Flavour Industry
While specific applications require careful verification, compounds with similar structural motifs are sometimes explored for their potential in the fragrance and flavour industry due to their aromatic nature.
| Molecular weight | 150.17 |
|---|---|
| Linear formula | CH3OC6H4COCH3 |
| Assay | 99% |
| Grade | purum |
| Boiling point | 152-154 °C/26 mmHg(lit.) |
| Solubility | H2O: soluble2.474 g/L at 20 °C |
| Melting point | 36-38 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 138 °C / 280.4 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-38 |
| Safety statements (S) | 37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Methoxyacetophenone used for?
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4′-Methoxyacetophenone is primarily used as a building block and intermediate in organic synthesis, including the preparation of pharmaceuticals and other fine chemicals.
What are the CAS number and chemical formula for 4′-Methoxyacetophenone?
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The CAS number for 4′-Methoxyacetophenone is 100-06-1, and its linear chemical formula is CH3OC6H4COCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Methoxyacetophenone with a minimum purity of 99%, graded as 'purum'. We do not represent this product as USP, BP, or EP grade.
How should 4′-Methoxyacetophenone be handled safely?
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4′-Methoxyacetophenone is classified with GHS07 symbol and carries a 'Warning' signal word. It is harmful if swallowed (H302) and causes skin irritation (H315). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray.
Is 4′-Methoxyacetophenone a controlled substance?
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The provided data does not indicate that 4′-Methoxyacetophenone (CAS: 100-06-1) is a controlled substance.
How is 4′-Methoxyacetophenone packed and exported?
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Tech Serve Solutions, a specialist global supplier and exporter, ensures appropriate packaging for chemical compounds like 4′-Methoxyacetophenone, adhering to international shipping regulations for safe and secure export.
How can I request a quote or sample of 4′-Methoxyacetophenone?
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To request a quote or sample of 4′-Methoxyacetophenone, please contact our sales team through the provided channels on the Tech Serve Solutions website.
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