4′-Methoxy-2-chloroacetophenone
4′-Methoxy-2-chloroacetophenone (CAS: 2196-99-8) is a halogenated acetophenone derivative with the chemical formula C9H9ClO2 and a molecular weight of 184.62 g/mol. This compound serves as a valuable building block in organic synthesis. It is characterised by its ketone and aryl halide functionalities, making it amenable to various chemical transformations in the development of more complex molecules, particularly within the pharmaceutical and fine chemical industries.
- IUPAC
- 2-Chloro-1-(4-methoxyphenyl)ethanone,4-(Chloroacetyl)anisole,4-Methoxyphenacyl chloride
- Synonyms
- 2-Chloro-1-(4-methoxyphenyl)ethanone4-(Chloroacetyl)anisole4-Methoxyphenacyl chloride

Organic Synthesis Intermediate
This compound is frequently employed as an intermediate in the synthesis of various organic compounds. Its reactive chloroacetyl group and methoxyphenyl moiety allow for diverse chemical modifications, facilitating the construction of complex molecular architectures.
Pharmaceutical Research and Development
As a building block, 4′-Methoxy-2-chloroacetophenone is utilised in the research and development of novel pharmaceutical agents. It can be incorporated into synthetic routes for potential drug candidates, leveraging its structural features for biological activity exploration.
Fine Chemical Production
The compound finds application in the production of fine chemicals where specific structural elements are required. Its availability as a research-grade chemical supports its use in specialised chemical manufacturing processes.
| Molecular weight | 184.62 |
|---|---|
| Empirical formula | C9H9ClO2 |
| Assay | 97% |
| Melting point | 96-100 °C |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Methoxy-2-chloroacetophenone used for?
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4′-Methoxy-2-chloroacetophenone (CAS: 2196-99-8) is primarily used as a building block and intermediate in organic synthesis, particularly in the research and development of pharmaceutical agents and fine chemicals.
What are the CAS number and chemical formula for 4′-Methoxy-2-chloroacetophenone?
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The CAS number for 4′-Methoxy-2-chloroacetophenone is 2196-99-8, and its chemical formula is C9H9ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Methoxy-2-chloroacetophenone with a minimum assay of 97%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.
What are the primary safety hazards associated with 4′-Methoxy-2-chloroacetophenone?
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4′-Methoxy-2-chloroacetophenone is classified as dangerous. It causes severe skin burns and eye damage (H314) and is harmful if swallowed (H302). Appropriate personal protective equipment, including gloves, eye protection, and protective clothing, must be worn when handling this substance.
How is 4′-Methoxy-2-chloroacetophenone packed, shipped, and exported?
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Tech Serve Solutions packs and ships 4′-Methoxy-2-chloroacetophenone in compliance with international regulations for hazardous materials. As a UN 3261, Class 8, Packing Group II substance, it is exported under strict guidelines.
How can I request a sample or quote for 4′-Methoxy-2-chloroacetophenone?
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To request a sample or a quote for 4′-Methoxy-2-chloroacetophenone, please contact our sales team through the website or by calling our main office. Please provide your contact details and the quantity required.
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