YM 976
YM 976 (CAS: 191219-80-4) is a chemical compound with the molecular formula C17H16N3OCl and a molecular weight of 313.78 g/mol. This compound, typically appearing as a yellow solid, is recognised for its role in biochemical research, particularly as an inhibitor in cell signalling pathways. It serves as a valuable tool for scientists investigating cyclic nucleotide metabolism and related cellular processes.
- IUPAC
- 4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one

Phosphodiesterase IV Inhibition
YM 976 acts as a selective inhibitor of Phosphodiesterase IV (PDE4), an enzyme crucial for the regulation of cyclic adenosine monophosphate (cAMP) levels within cells. This makes it useful for studying cellular signalling pathways regulated by cAMP.
Cell Signalling Research
As a modulator of cyclic nucleotide metabolism, YM 976 is employed in research settings to investigate cellular responses, particularly within the fields of neuroscience and cell biology. Its specific inhibitory action aids in dissecting complex signalling cascades.
Biochemical Assays
The compound is utilised as a reagent in biochemical assays to probe enzyme activity and cellular responses. Its defined inhibitory profile allows for precise experimental design in investigating PDE4-related functions.
| Molecular weight | 313.78 |
|---|---|
| Empirical formula | C17H16N3OCl |
| Assay | ≥98% (HPLC) |
| Colour | yellow |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | 2-8°C |
| Melting point | 132.7-134.0 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is YM 976 primarily used for?
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YM 976 is primarily used as a selective Phosphodiesterase IV (PDE4) inhibitor for research in cell signalling, cyclic nucleotide metabolism, neuroscience, and cell biology.
What are the CAS number and molecular formula for YM 976?
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The CAS number for YM 976 is 191219-80-4, and its molecular formula is C17H16N3OCl.
What grade and purity does Tech Serve Solutions supply for YM 976?
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Tech Serve Solutions supplies YM 976 with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling requirements for YM 976?
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YM 976 requires the use of eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a WGK Germany rating of 3, indicating it is hazardous to water.
How is YM 976 typically packed and exported?
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YM 976 is carefully packed to maintain its integrity during storage and transit. As a global supplier, TSS exports this chemical, adhering to all relevant shipping regulations.
How can I request a sample or a quote for YM 976?
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To request a sample or a quote for YM 976, please contact our sales department through the website or direct email, providing your specific requirements.
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