4-Nitro-3-(trifluoromethyl)benzoic acid

CAS 320-38-7C8H4F3NO4Chemical Synthesis

4-Nitro-3-(trifluoromethyl)benzoic acid (CAS 320-38-7), with the molecular formula C8H4F3NO4 and a molecular weight of 235.12 g/mol, is a crucial organic building block. This compound serves as a key intermediate in the synthesis of various fine chemicals and pharmaceutical agents. Its specific structure, featuring both nitro and trifluoromethyl groups on a benzoic acid core, makes it valuable for introducing these functionalities into more complex molecules through established chemical transformations.

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4-Nitro-3-(trifluoromethyl)benzoic acid (C8H4F3NO4) — chemical structure, CAS 320-38-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksCarbonyl CompoundsCarboxylic AcidsChemical Synthesis

01 /Applications

Organic Synthesis Intermediate

4-Nitro-3-(trifluoromethyl)benzoic acid is widely used as a starting material or intermediate in multi-step organic syntheses. Its reactive functional groups allow for diverse chemical modifications, leading to the creation of novel compounds.

Pharmaceutical Research

This compound finds application in the development of new pharmaceutical drug candidates. It can be incorporated into molecular scaffolds designed to interact with specific biological targets.

Material Science

The unique electronic and structural properties imparted by the trifluoromethyl and nitro groups can be exploited in the design of advanced materials, potentially for electronic or optical applications.

02 /Properties

Molecular weight	235.12
Empirical formula	C8H4F3NO4
Assay	97%
Melting point	160-164 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	2
Hazard codes (EU)	Xn
Risk statements (R)	22-36-43
Safety statements (S)	26-36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

320-38-7

MDL number

MFCD06200716

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Nitro-3-(trifluoromethyl)benzoic acid used for?

4-Nitro-3-(trifluoromethyl)benzoic acid is primarily used as an intermediate in organic synthesis, particularly in the pharmaceutical and fine chemical industries for creating more complex molecules.

What is the CAS number and formula for 4-Nitro-3-(trifluoromethyl)benzoic acid?

The CAS number is 320-38-7 and the molecular formula is C8H4F3NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-Nitro-3-(trifluoromethyl)benzoic acid with a purity of 97%. We do not represent this product as USP, EP, or BP grade.

How should 4-Nitro-3-(trifluoromethyl)benzoic acid be handled?

Based on its GHS classification, this compound is harmful if swallowed (H302), may cause an allergic skin reaction (H317), and causes serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, faceshields, and gloves, should be worn. Ensure adequate ventilation.