(−)-Caryophyllene oxide
(−)-Caryophyllene oxide (CAS: 1139-30-6), a chiral epoxide with formula C15H24O and molecular weight 220.35 g/mol, serves as a valuable building block in organic synthesis. It is particularly useful in asymmetric synthesis due to its defined stereochemistry. Its applications span chemical synthesis and the development of complex organic molecules, making it a key intermediate for researchers and industrial chemists.
- IUPAC
- (−)-Epoxycaryophyllene,(1R,4R,6R,10S)-9-Methylene-4,12,12-trimethyl-5-oxatricyclo[8.2.0.04,6]dodecane

Asymmetric Synthesis
Utilised as a chiral building block in stereoselective reactions, enabling the synthesis of enantiomerically enriched compounds.
Organic Synthesis
Serves as a versatile intermediate for constructing complex organic molecules and natural product analogues.
Epoxide Chemistry
Engages in ring-opening reactions characteristic of epoxides, leading to functionalised derivatives.
| Molecular weight | 220.35 |
|---|---|
| Empirical formula | C15H24O |
| Assay | ≥99.0% (sum of enantiomers, GC) |
| Optical activity | [α]20/D −71±1°, c = 2% in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 62-63 °C(lit.)62-63 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Caryophyllene oxide used for?
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(–)-Caryophyllene oxide is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in general organic synthesis for creating complex molecules.
What is the CAS number and formula for (–)-Caryophyllene oxide?
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The CAS number is 1139-30-6 and the empirical formula is C15H24O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-Caryophyllene oxide with an assay of ≥99.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade.
How should (–)-Caryophyllene oxide be handled?
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(–)-Caryophyllene oxide is classified as an irritant (H315, H319). Handle with appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves. Avoid contact with skin and eyes, and ensure good ventilation.
How is (–)-Caryophyllene oxide shipped and exported?
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Tech Serve Solutions exports chemicals globally. Packaging and shipping comply with international regulations for hazardous materials. Please contact us for specific export details.
How can I request a sample or quote for (–)-Caryophyllene oxide?
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To request a sample or a quotation, please use the contact form on our website or email our sales department, referencing the product name and CAS number 1139-30-6.
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