(−)-Camphor-10-sulfonic acid
(−)-Camphor-10-sulfonic acid (CAS: 35963-20-3, C10H16O4S) is a chiral sulfonic acid derived from camphor. It is a strong chiral acid recognised for its utility in asymmetric synthesis and as a resolving agent for separating enantiomers. With a molecular weight of 232.30 g/mol, this compound serves as a valuable building block in organic synthesis and is employed in derivatisation for analytical purposes, particularly in chromatography.
- IUPAC
- (1R)-(−)-Camphor-10-sulfonic acid
Asymmetric Synthesis
This chiral acid is a key reagent in asymmetric synthesis, enabling the stereoselective preparation of optically active compounds. Its ability to form diastereomeric salts is crucial for the resolution of racemic mixtures.
Chiral Resolving Agent
(−)-Camphor-10-sulfonic acid is widely used to resolve chiral bases and amines. It forms crystalline diastereomeric salts that can be separated by fractional crystallisation, yielding enantiomerically pure compounds.
Derivatisation Reagent
In analytical chemistry, it is employed as a derivatisation reagent, especially for enhancing the detectability of compounds in chromatographic techniques like HPLC. This facilitates the accurate quantification and separation of analytes.
Organic Synthesis Intermediate
As an organic building block, it finds application in the synthesis of complex organic molecules and pharmaceutical intermediates where chirality is a critical factor for biological activity.
| Molecular weight | 232.30 |
|---|---|
| Empirical formula | C10H16O4S |
| Assay | ≥98.0% (T) |
| Grade | purum |
| Optical activity | [α]20/D −21.5±1°, c = 10% in H2O |
| Melting point | 198 °C (dec.)(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Camphor-10-sulfonic acid used for?
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(–)-Camphor-10-sulfonic acid is primarily used in asymmetric synthesis, as a chiral resolving agent for separating enantiomers, and as a derivatisation reagent in analytical chemistry, particularly for HPLC.
What is the CAS number and molecular formula for (–)-Camphor-10-sulfonic acid?
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The CAS number is 35963-20-3, and the molecular formula is C10H16O4S.
What grade and purity does Tech Serve Solutions supply for (–)-Camphor-10-sulfonic acid?
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Tech Serve Solutions supplies (–)-Camphor-10-sulfonic acid in 'purum' grade with an assay of ≥98.0% (T). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for (–)-Camphor-10-sulfonic acid?
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(–)-Camphor-10-sulfonic acid is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, must be used. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
Can I request a sample or quote for (–)-Camphor-10-sulfonic acid?
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Yes, you can request a sample or a quote for (–)-Camphor-10-sulfonic acid through our website or by contacting our sales team directly.
How is (–)-Camphor-10-sulfonic acid packed, shipped, or exported?
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(–)-Camphor-10-sulfonic acid is packed and shipped in compliance with international regulations for hazardous materials, including UN 3261 8 / PGII. TSS is experienced in global export.
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