2-Chloro-1-fluoro-4-nitrobenzene
2-Chloro-1-fluoro-4-nitrobenzene (CAS: 350-30-1; Formula: ClC6H3(F)NO2) is a halogenated nitroaromatic compound with a molecular weight of 175.54 g/mol. This chemical serves as a versatile building block in organic synthesis, particularly for introducing fluorinated and chlorinated aromatic moieties. Its utility is demonstrated in the preparation of complex heterocyclic compounds and intermediates for various chemical research applications. Tech Serve Solutions supplies this reagent with a minimum assay of 98%.
Synthesis of Heterocyclic Compounds
2-Chloro-1-fluoro-4-nitrobenzene is employed in the synthesis of fused heterocyclic systems. It has been notably used in the preparation of benzoimidolones on Ameba resin.
Pharmaceutical Intermediate Synthesis
This compound acts as a valuable intermediate in the development of novel organic molecules. Its structure allows for further functionalisation, contributing to the synthesis of complex targets such as methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate.
Fluorinated Building Block
As an aryl fluorinated building block, it enables the incorporation of fluorine atoms into organic structures, a key feature in the design of modern pharmaceuticals and materials.
| Molecular weight | 175.54 |
|---|---|
| Linear formula | ClC6H3(F)NO2 |
| Assay | 98% |
| Application | 2-Chloro-1-fluoro-4-nitrobenzene has been used in synthesis of:• benzoimidolones on Ameba resin1• methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate2 |
| Melting point | 40-42 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-1-fluoro-4-nitrobenzene used for?
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2-Chloro-1-fluoro-4-nitrobenzene is used as a building block in organic synthesis, particularly for preparing heterocyclic compounds and other complex molecules in chemical research.
What is the CAS number and formula for 2-Chloro-1-fluoro-4-nitrobenzene?
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The CAS number is 350-30-1, and the chemical formula is ClC6H3(F)NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-1-fluoro-4-nitrobenzene with a minimum assay of 98%. It is supplied as a research or technical grade material and is not represented as USP, BP, or EP grade.
How should 2-Chloro-1-fluoro-4-nitrobenzene be handled safely?
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Handling requires appropriate personal protective equipment including a dust mask (N95 recommended), eyeshields, and gloves. It is a Danger product, harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335).
Does Tech Serve Solutions export 2-Chloro-1-fluoro-4-nitrobenzene?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-1-fluoro-4-nitrobenzene.
How can I request a quote or sample?
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To request a quote or sample for 2-Chloro-1-fluoro-4-nitrobenzene, please contact our sales team through the website or by phone.
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