Yohimbine hydrochloride
Yohimbine hydrochloride (CAS 65-19-0), a chemical formula of C21H26N2O3 · HCl and a molecular weight of 390.90 g/mol, is supplied as a white to off-white powder. It is a well-known alkaloid and adrenergic antagonist. Primarily utilised in research settings, it serves as a valuable tool in cell biology, neuroscience, and biochemical studies investigating neurotransmission and receptor interactions.
- IUPAC
- 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride
Neuroscience Research
Yohimbine hydrochloride is frequently used in neuroscientific research to study adrenergic receptor function, particularly alpha-2 adrenergic receptors, and their role in neurotransmission and various neurological processes.
Pharmacological Investigations
As an alpha-adrenergic antagonist, it is employed in pharmacological studies to understand receptor-ligand interactions and to investigate potential therapeutic targets in conditions related to the sympathetic nervous system.
Biochemical Assays
This compound serves as a reagent in biochemical assays to probe cellular signaling pathways and the function of G-protein coupled receptors (GPCRs).
| Molecular weight | 390.90 |
|---|---|
| Empirical formula | C21H26N2O3 · HCl |
| Assay | ≥98% (TLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | H2O: soluble10 mg/mL |
| Melting point | 288-290 °C (dec.)(lit.) |
Hazard statements
- H300Fatal if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Yohimbine hydrochloride (CAS 65-19-0) typically used for?
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Yohimbine hydrochloride is primarily used in scientific research, including neuroscience, pharmacology, and cell biology, to study adrenergic receptors and neurotransmission.
What are the CAS number and formula for Yohimbine hydrochloride?
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The CAS number for Yohimbine hydrochloride is 65-19-0, and its formula is C21H26N2O3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Yohimbine hydrochloride with an assay of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.
How should Yohimbine hydrochloride be handled safely?
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Yohimbine hydrochloride is a Danger substance (GHS06) with hazards H300, H311, and H331, meaning it is toxic if swallowed, in contact with skin, or if inhaled. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge, must be used. Handle only in well-ventilated areas and seek immediate medical attention if exposure occurs.
Is Yohimbine hydrochloride a controlled substance?
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Yes, Yohimbine hydrochloride is classified under UN 1544, ADR Class 6.1, Packing Group II, indicating it is a toxic substance requiring specific handling and transport regulations.
How is Yohimbine hydrochloride packed, shipped, and exported?
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Tech Serve Solutions packs and exports Yohimbine hydrochloride in compliance with all relevant national and international regulations for hazardous materials.
How can I request a sample or quote for Yohimbine hydrochloride?
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To request a sample or a quote for Yohimbine hydrochloride, please contact our sales team through the website or direct inquiry channels.
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