Z-Phe-Bt
Z-Phe-Bt (CAS: 769922-77-2), with the molecular formula C23H20N4O3 and a molecular weight of 400.43 g/mol, is a benzotriazole amino acid derivative. It serves as a versatile reagent in chemical synthesis, particularly within peptide chemistry. Its primary applications include the preparation of polypeptides, peptidomimetics, and tagged peptides, making it valuable for researchers in chemical biology and pharmaceutical development.
- IUPAC
- (S)-N-Z-1-Benzotriazolylcarbonyl-2-phenylethylamine,(S)-Benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-ylcarbamate
- Synonyms
- (S)-N-Z-1-Benzotriazolylcarbonyl-2-phenylethylamine(S)-Benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-ylcarbamate
Peptide Synthesis
Z-Phe-Bt is employed in the synthesis of peptides and their analogues. It facilitates the formation of polypeptides and peptidomimetics, including aminoxypeptides and depsipeptides.
Tagged Peptide Preparation
This compound is utilised for the preparation of tagged peptides and peptidomimetics. It is particularly useful for conjugating fluorescent labels to peptide structures.
Peptide Conjugate Synthesis
Z-Phe-Bt enables the synthesis of diverse peptide conjugates. It can be used to form N, O, S, and C linked peptide conjugates, expanding its utility in biochemical research.
| Molecular weight | 400.43 |
|---|---|
| Empirical formula | C23H20N4O3 |
| Storage temperature | −20°C |
| Application | Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:• Polypeptidal benzotriazolides1• Peptidomimetics, such as aminoxypeptides2, depsipeptides3 and heterocyclic peptidomimetics4• Tagged peptides and peptidomimetics, particularly those with fluorescent labels5,6• N, O, S, and C linked peptide conjugates6 |
| Melting point | 143-150 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Phe-Bt used for?
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Z-Phe-Bt is used in chemical synthesis, primarily for the preparation of peptides, peptidomimetics, and tagged peptides, as well as peptide conjugates.
What are the CAS number and formula for Z-Phe-Bt?
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The CAS number for Z-Phe-Bt is 769922-77-2, and its empirical formula is C23H20N4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-Phe-Bt for research purposes. The specific grade and purity are available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Z-Phe-Bt?
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Z-Phe-Bt is classified with GHS07 symbol and a 'Warning' signal word, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, avoiding dust formation and ensuring good ventilation. Precautionary statements include P261 (Avoid breathing dust) and P305 + P351 + P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing).
How is Z-Phe-Bt typically stored and shipped?
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Z-Phe-Bt is recommended to be stored at -20°C. It is packaged and exported according to standard chemical handling and shipping regulations.
How can I request a quote or sample for Z-Phe-Bt?
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To request a quote or a sample of Z-Phe-Bt, please contact the Tech Serve Solutions sales team through our website or by phone.
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