Z-Pro-OH
Z-L-Proline (CAS: 1148-11-4), a derivative of the amino acid proline with the molecular formula C13H15NO4, is a key intermediate in peptide synthesis and chemical biology research. Characterised by its optical activity ([α]20/D −42°, c = 2 in ethanol), this compound is crucial for building complex peptide chains and probing biological systems. Supplied with an assay of 99%, it meets stringent requirements for advanced chemical applications.
- IUPAC
- Z-L-Proline

Peptide Synthesis
Z-L-Proline is an essential N-protected amino acid derivative used in solid-phase and solution-phase peptide synthesis. It allows for the controlled stepwise assembly of peptide sequences, forming the backbone of many biologically active molecules.
Chemical Biology Research
This compound serves as a valuable building block in chemical biology for creating modified peptides or peptidomimetics. Its incorporation can help elucidate protein structure-function relationships and develop novel therapeutic agents.
Organic Synthesis Intermediate
As a chiral proline derivative, Z-L-Proline is employed in asymmetric synthesis for creating complex organic molecules. It acts as a versatile intermediate in multi-step synthetic pathways.
| Molecular weight | 249.26 |
|---|---|
| Empirical formula | C13H15NO4 |
| Assay | 99% |
| Optical activity | [α]20/D −42°, c = 2 in ethanol |
| Melting point | 76-78 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-L-Proline used for?
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Z-L-Proline is primarily used as a building block in peptide synthesis and as an intermediate in chemical biology and organic synthesis.
What is the CAS number and formula for Z-L-Proline?
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The CAS number for Z-L-Proline is 1148-11-4, and its molecular formula is C13H15NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-L-Proline with an assay of 99%. This is typically considered a research or technical grade, and TSS does not represent it as USP, BP, or EP grade unless explicitly stated.
What are the safety and handling recommendations for Z-L-Proline?
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Handling Z-L-Proline requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK rating of 3 in Germany, indicating a significant hazard to water.
Is Z-L-Proline a controlled substance?
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The provided data does not indicate that Z-L-Proline (CAS: 1148-11-4) is a controlled substance.
How is Z-L-Proline shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals and reagents. Z-L-Proline is carefully packaged and exported in compliance with international shipping regulations for chemical substances.
How can I request a quote or sample of Z-L-Proline?
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To request a quote or sample of Z-L-Proline, please contact the Tech Serve Solutions sales team through our website or by phone.
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