Z-Ser(tBu)-OH
Z-Ser(tBu)-OH, with CAS number 1676-75-1 and molecular formula C15H21NO5, is a protected derivative of the amino acid serine. This compound, featuring a tert-butyl ester and a benzyloxycarbonyl (Z) protecting group on the amine, is a valuable building block in peptide synthesis. Its protected nature allows for controlled coupling reactions in the creation of complex peptide chains, finding utility in chemical synthesis and research applications.
- IUPAC
- N-Z-O-tert-butyl-L-serine
- Synonyms
- N-Benzyloxycarbonyl-O-tert-butyl-L-serine
Peptide Synthesis
Z-Ser(tBu)-OH serves as a crucial protected amino acid in solid-phase and solution-phase peptide synthesis. The tert-butyl ester protects the carboxyl group, while the Z-group protects the amine, enabling selective deprotection and controlled chain elongation.
Chemical Synthesis
This compound is employed as a versatile intermediate in organic and medicinal chemistry. Its structure allows for further modifications, contributing to the synthesis of novel compounds and potential pharmaceutical agents.
Chemical Biology
Researchers in chemical biology may utilise Z-Ser(tBu)-OH for constructing labelled peptides or peptidomimetics used in studying biological processes and protein interactions.
| Molecular weight | 295.33 |
|---|---|
| Empirical formula | C15H21NO5 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Ser(tBu)-OH used for?
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Z-Ser(tBu)-OH is primarily used as a protected building block in peptide synthesis and as an intermediate in chemical synthesis and chemical biology research.
What is the CAS number and formula for Z-Ser(tBu)-OH?
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The CAS number for Z-Ser(tBu)-OH is 1676-75-1, and its molecular formula is C15H21NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-Ser(tBu)-OH with an assay of ≥98.0% as determined by TLC. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Z-Ser(tBu)-OH be handled and stored?
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According to the safety data, handle Z-Ser(tBu)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Consult the safety data sheet for full handling and storage recommendations.
Is Z-Ser(tBu)-OH classified as a hazardous substance?
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Z-Ser(tBu)-OH has a WGK Germany classification of 3, indicating it is hazardous to water. Appropriate precautions should be taken during handling and disposal to prevent environmental contamination.
How is Z-Ser(tBu)-OH packed and exported?
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Tech Serve Solutions reliably packs and exports fine chemicals globally. Specific packaging details will be provided upon order confirmation, adhering to international shipping regulations.
How can I request a sample or quote for Z-Ser(tBu)-OH?
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To request a sample or quote for Z-Ser(tBu)-OH, please contact our sales team through the website or by phone, providing your specific requirements.
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