Z-Ser-OH
Z-Ser-OH (CAS: 1145-80-8) is a protected amino acid derivative, specifically Z-L-Serine. With a molecular weight of 239.22 g/mol and a linear formula of HOCH2CH(NHCO2CH2C6H5)CO2H, it is primarily utilised as a key building block in peptide synthesis. Additionally, it serves as a starting material for synthesising various alpha-amino acids through beta-lactone intermediates. This compound is supplied by TSS with a purity of ≥99%.
- IUPAC
- Carbobenzyloxy-L-serine,Z-L-Serine
- Synonyms
- Carbobenzyloxy-L-serineZ-L-Serine

Peptide Synthesis
Z-Ser-OH is a crucial protected amino acid derivative extensively used as a building block in the synthesis of peptides. Its structure facilitates controlled chain elongation in solid-phase or solution-phase peptide synthesis.
Amino Acid Synthesis
This compound acts as a valuable starting material for the laboratory synthesis of various alpha-amino acids. It is particularly noted for its utility in pathways involving beta-lactone intermediates, enabling the creation of complex amino acid structures.
Chemical Biology Research
As a derivative of serine, Z-Ser-OH finds application in chemical biology research, where modified amino acids are employed to probe biological processes or create novel biomolecules.
| Molecular weight | 239.22 |
|---|---|
| Linear formula | HOCH2CH(NHCO2CH2C6H5)CO2H |
| Assay | ≥99% |
| Optical activity | [α]20/D +5.8°, c = 2.7 in acetic acid |
| Application | Building block in peptide synthesis; Starting material for the synthesis of various α-amino acids via the β-lactone1 |
| Melting point | 116-119 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Ser-OH used for?
+
Z-Ser-OH is primarily used as a building block in peptide synthesis and as a starting material for the synthesis of various alpha-amino acids via beta-lactone intermediates.
What is the CAS number and molecular formula for Z-Ser-OH?
+
The CAS number for Z-Ser-OH is 1145-80-8, and its linear formula is HOCH2CH(NHCO2CH2C6H5)CO2H.
What grade and purity does Tech Serve Solutions supply for Z-Ser-OH?
+
Tech Serve Solutions supplies Z-Ser-OH with a purity of ≥99%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for Z-Ser-OH?
+
Z-Ser-OH is classified under WGK Germany 3, indicating a high hazard level. Users should consult the Safety Data Sheet (SDS) for comprehensive handling, storage, and disposal information to mitigate risks.
Is Z-Ser-OH a controlled substance?
+
The provided data does not indicate that Z-Ser-OH is a controlled substance.
How is Z-Ser-OH packed, shipped, and exported?
+
Z-Ser-OH is carefully packed according to industry standards to ensure safe transit. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a quote or sample for Z-Ser-OH?
+
To request a quote or a sample of Z-Ser-OH, please contact our sales department through the website or by phone, providing your specific requirements.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis