1-(3,4,5-Trimethoxybenzyl)piperazine hydrochloride
1-(3,4,5-Trimethoxybenzyl)piperazine hydrochloride is the hydrochloride salt of a substituted piperazine building block, in which a piperazine ring carries a 3,4,5-trimethoxybenzyl group. The free base (CAS 52146-35-7) has the formula C14H22N2O3 and a molar mass of 266.34 g/mol; the salt is described as C14H22N2O3 · xHCl. Supplied at a minimum assay of 95% (HPLC), it is used principally as a heterocyclic building block and intermediate in chemical synthesis and medicinal-chemistry research. Tech Serve Solutions supplies it as a research-grade material.
- Synonyms
- 1-(3,4,5-Trimethoxybenzyl)piperazine hydrochloride1-(3,4,5-Trimethoxybenzyl)piperazine HCl1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine hydrochloride1-(3,4,5-Trimethoxybenzyl)piperazine, free base CAS 52146-35-7C14H22N2O3 · xHCl
Heterocyclic building block
Serves as a piperazine-based building block for chemical synthesis, providing a basic, di-nitrogen ring that can be further functionalised at the free N-H position.
Pharmaceutical and medicinal-chemistry intermediate
The N-substituted piperazine scaffold combined with a 3,4,5-trimethoxybenzyl group is a recognised motif in medicinal chemistry, making this compound useful as an intermediate in research-scale synthesis of more elaborate molecules.
Research and laboratory use
Used as a reference building block and reagent in discovery and process-development laboratories where a trimethoxybenzyl piperazine fragment is required.
Library and analogue synthesis
Suitable for the preparation of compound libraries and structural analogues, where the piperazine nitrogen can be acylated, alkylated or otherwise derivatised.
| Molecular weight | 266.34 (free base basis) |
|---|---|
| Empirical formula | C14H22N2O3 · xHCl |
| Assay | ≥95%≥95.0% (HPLC) |
| Impurities tested | ≤5.0% water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3,4,5-Trimethoxybenzyl)piperazine hydrochloride used for?
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It is used mainly as a heterocyclic building block and synthetic intermediate. The piperazine ring with its 3,4,5-trimethoxybenzyl substituent is a useful fragment in medicinal-chemistry and general research synthesis, where the free piperazine nitrogen can be further derivatised.
What is the CAS number and molecular formula of 1-(3,4,5-Trimethoxybenzyl)piperazine hydrochloride?
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The free base carries CAS number 52146-35-7, with molecular formula C14H22N2O3 and a molar mass of 266.34 g/mol. The hydrochloride salt supplied here is described as C14H22N2O3 · xHCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum assay of 95% (≥95.0% by HPLC), with water content of ≤5.0%. It is offered as a technical/research-grade material; we do not represent it as USP, BP or EP pharmacopoeial grade unless separately specified.
What are the safety and handling requirements?
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Handle as a laboratory chemical using appropriate personal protective equipment, including eye shields, gloves and an N95 (US) or P1 (EN143) respirator filter where dust may be generated. The substance is assigned German water-hazard class WGK 3 (severely hazardous to water), so prevent any release to drains, soil or watercourses. Always consult the Safety Data Sheet before use.
How is 1-(3,4,5-Trimethoxybenzyl)piperazine hydrochloride packed, shipped and exported?
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It is packed in sealed, clearly labelled containers sized to the order, from research quantities upward, with full documentation. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant international shipping with the appropriate certificates and an accompanying Safety Data Sheet.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and export options. Samples can be requested for qualification, subject to availability.
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