4-Hydroxymephenytoin
4-Hydroxymephenytoin (CAS: 61837-65-8, C12H14N2O3) is a chemical compound with a molecular weight of 234.25 g/mol. This substance is primarily utilised in pharmacological research to investigate drug effects on metabolisation and its impact on *in vitro* cytochrome P450 activity in microsomes. It also serves as a valuable analyte in specific electron-capture gas chromatography procedures, aiding analytical investigations.
- IUPAC
- (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin,(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione

Pharmacological Research
Investigate the drug effects of 4-Hydroxymephenytoin on metabolisation processes. Study its impact on *in vitro* cytochrome P450 activity within microsomes.
Analytical Chemistry
Utilise 4-Hydroxymephenytoin as an analyte in electron-capture gas chromatography procedures. This facilitates precise analytical investigations and measurements.
Chemical Synthesis
Employ 4-Hydroxymephenytoin as a heterocyclic building block in organic synthesis. Its structure makes it suitable for constructing more complex molecules.
| Molecular weight | 234.25 |
|---|---|
| Empirical formula | C12H14N2O3 |
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: >5 mg/mL |
| Storage temperature | 2-8°C |
| Application | Pharmacological activity investigating:• The drug effects on metabolization1• In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3 |
| Melting point | 153-154 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxymephenytoin primarily used for?
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4-Hydroxymephenytoin is used in pharmacological research to investigate drug effects on metabolisation and *in vitro* cytochrome P450 activity, and as an analyte in electron-capture gas chromatography procedures.
What are the CAS number and molecular formula for 4-Hydroxymephenytoin?
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The CAS number for 4-Hydroxymephenytoin is 61837-65-8, and its molecular formula is C12H14N2O3.
What grade and purity does Tech Serve Solutions supply for 4-Hydroxymephenytoin?
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Tech Serve Solutions supplies 4-Hydroxymephenytoin with a minimum purity of 98% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for 4-Hydroxymephenytoin?
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Handling 4-Hydroxymephenytoin requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. Consult the Safety Data Sheet for comprehensive handling information.
How is 4-Hydroxymephenytoin typically stored and shipped?
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4-Hydroxymephenytoin should be stored at 2-8°C. Tech Serve Solutions ensures secure packaging and global export for this chemical.
How can I request a quote or sample of 4-Hydroxymephenytoin?
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To request a quote or sample of 4-Hydroxymephenytoin, please contact our sales team through the website or by phone.
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