4-Hydroxyisophthalic acid
4-Hydroxyisophthalic acid (CAS 636-46-4) is an organic compound with the formula HOC<sub>6</sub>H<sub>3</sub>-1,3-(CO<sub>2</sub>H)<sub>2</sub> and a molecular weight of 182.13 g/mol. It is a derivative of isophthalic acid featuring a hydroxyl group. This aromatic dicarboxylic acid functions as a versatile building block in organic synthesis, particularly in the creation of polymers, resins, and specialised chemical intermediates. Its defined structure makes it valuable for applications requiring specific molecular architecture.
- Synonyms
- 3,5-Dicarboxy-phenol4-Hydroxybenzene-1,3-dicarboxylic acid

Polymer Synthesis
4-Hydroxyisophthalic acid serves as a monomer or co-monomer in the synthesis of specialty polyesters and polyamides. Its incorporation can modify polymer properties such as thermal stability and solubility.
Organic Synthesis Intermediate
It acts as a key intermediate for the preparation of more complex organic molecules and fine chemicals. The hydroxyl and carboxylic acid functionalities allow for diverse chemical transformations.
Material Science Research
The compound is utilised in academic and industrial research for developing novel materials with tailored characteristics, including advanced resins and functional organic frameworks.
| Molecular weight | 182.13 |
|---|---|
| Linear formula | HOC6H3-1,3-(CO2H)2 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxyisophthalic acid used for?
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4-Hydroxyisophthalic acid is primarily used as a building block in organic synthesis for creating polymers, resins, and specialised chemical intermediates. It is also employed in material science research.
What are the CAS number and formula for 4-Hydroxyisophthalic acid?
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The CAS number is 636-46-4 and the linear formula is HOC<sub>6</sub>H<sub>3</sub>-1,3-(CO<sub>2</sub>H)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxyisophthalic acid typically at a purity suitable for research and chemical synthesis applications. Please refer to the product's Certificate of Analysis for specific assay details. We do not represent this product as USP, BP, or EP grade.
How should 4-Hydroxyisophthalic acid be handled?
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4-Hydroxyisophthalic acid is classified as an irritant. Handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area. Avoid inhalation, ingestion, and contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and hazard information (H315, H319, H335).
Is 4-Hydroxyisophthalic acid a controlled substance?
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Based on the provided data, 4-Hydroxyisophthalic acid is not listed as a controlled substance.
How is 4-Hydroxyisophthalic acid shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of chemicals, adhering to international shipping and export regulations. Packaging is designed to ensure safe transit.
How can I request a quote or sample?
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To request a quote or a sample of 4-Hydroxyisophthalic acid, please use the contact form on our website or contact our sales department directly.
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