4-Hydroxycoumarin
4-Hydroxycoumarin (CAS 1076-38-6, C9H6O3, MW: 162.14) is a coumarin derivative with significant applications in organic synthesis and biochemistry. Its molecular structure is 4-hydroxy-1-benzopyran-2-one. This compound serves as a crucial building block for the synthesis of various biologically active molecules, including anticoagulants and fluorescent probes, making it a valuable reagent for research and development in chemical and cell biology studies.
- IUPAC
- 4-Hydroxy-1-benzopyran-2-one
Anticoagulant Precursor
4-Hydroxycoumarin is a key intermediate in the synthesis of vitamin K antagonist anticoagulants, such as warfarin and dicoumarol. These compounds are widely used in medicine to prevent and treat thromboembolic diseases.
Fluorescent Probe Synthesis
The inherent fluorescence of the coumarin scaffold makes 4-hydroxycoumarin a useful starting material for developing fluorescent dyes and probes. These can be employed in biological imaging and sensing applications.
Organic Synthesis Building Block
As a versatile heterocyclic building block, it is utilised in the construction of more complex organic molecules and novel chemical entities for various research purposes.
Biochemical Research
It is used in biochemical assays and studies, particularly those involving enzyme inhibition or the investigation of metabolic pathways related to coumarin derivatives.
| Molecular weight | 162.14 |
|---|---|
| Empirical formula | C9H6O3 |
| Assay | 98% |
| Melting point | 211-213 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Maoa(17161)rat ... Aldh1a2(116676) |
|---|---|
| Fluorescence | λem 373 nm in methanol |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxycoumarin used for?
+
4-Hydroxycoumarin is primarily used as a precursor for anticoagulant drugs, a building block in organic synthesis, and in the development of fluorescent probes for biochemical research.
What are the CAS number and formula for 4-Hydroxycoumarin?
+
The CAS number for 4-Hydroxycoumarin is 1076-38-6, and its molecular formula is C9H6O3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Hydroxycoumarin with a minimum assay of 98%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
How should 4-Hydroxycoumarin be handled safely?
+
Handle 4-Hydroxycoumarin with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as harmful if swallowed and causes skin and eye irritation.
Is 4-Hydroxycoumarin a controlled substance?
+
Based on the provided data, 4-Hydroxycoumarin is not indicated as a controlled or scheduled substance.
How is 4-Hydroxycoumarin packed and exported?
+
Tech Serve Solutions reliably packs and exports 4-Hydroxycoumarin globally to meet the needs of researchers and industrial clients.
How can I request a sample or quote for 4-Hydroxycoumarin?
+
To request a sample or a quote for 4-Hydroxycoumarin, please contact our sales team through the website or via the provided contact details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis