4′-Fluorobiphenyl-4-sulfonyl chloride
4′-Fluorobiphenyl-4-sulfonyl chloride (CAS: 116748-66-4) is a key organic intermediate with the molecular formula C12H8ClFO2S and a molecular weight of 270.71 g/mol. This fluorinated building block is essential for introducing the 4-fluorobiphenyl-4-sulfonyl moiety into more complex molecular structures. Its reactivity makes it a valuable reagent in organic synthesis, particularly for the development of novel compounds in pharmaceutical and materials science research.
- IUPAC
- 4-(4-Fluorophenyl)benzenesulfonyl chloride
Pharmaceutical Synthesis
Serves as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, enabling the introduction of fluorinated biphenyl functionalities.
Organic Synthesis Reagent
Used as a versatile building block for the construction of complex organic molecules, facilitating the formation of sulfonamide and sulfonate ester linkages.
Materials Science
Applicable in the development of advanced materials where the specific electronic or physical properties imparted by the fluorinated biphenyl group are desired.
| Molecular weight | 270.71 |
|---|---|
| Empirical formula | C12H8ClFO2S |
| Assay | 95% |
| Melting point | 80-85 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Fluorobiphenyl-4-sulfonyl chloride used for?
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4′-Fluorobiphenyl-4-sulfonyl chloride is primarily used as a building block in organic synthesis, particularly for the introduction of the 4-fluorobiphenyl-4-sulfonyl group in the development of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and formula for 4′-Fluorobiphenyl-4-sulfonyl chloride?
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The CAS number for 4′-Fluorobiphenyl-4-sulfonyl chloride is 116748-66-4, and its empirical formula is C12H8ClFO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Fluorobiphenyl-4-sulfonyl chloride with an assay of 95%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4′-Fluorobiphenyl-4-sulfonyl chloride be handled?
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4′-Fluorobiphenyl-4-sulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with extreme caution, wearing appropriate personal protective equipment including gloves, eye protection, and protective clothing. Ensure adequate ventilation.
Is 4′-Fluorobiphenyl-4-sulfonyl chloride a controlled substance?
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The provided data does not indicate that 4′-Fluorobiphenyl-4-sulfonyl chloride is a controlled substance.
How is 4′-Fluorobiphenyl-4-sulfonyl chloride shipped and exported?
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As a dangerous good (UN 3261, Class 8, Packing Group II), 4′-Fluorobiphenyl-4-sulfonyl chloride is shipped and exported in compliance with international regulations for hazardous materials transportation.
How can I request a sample or quote for 4′-Fluorobiphenyl-4-sulfonyl chloride?
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To request a sample or obtain a quotation for 4′-Fluorobiphenyl-4-sulfonyl chloride, please contact our sales department via the website or provided contact details.
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