4′-Fluoropropiophenone
4′-Fluoropropiophenone (CAS: 456-03-1), with the molecular formula FC<sub>6</sub>H<sub>4</sub>C(O)C<sub>2</sub>H<sub>5</sub> and a molecular weight of 152.17 g/mol, is a fluorinated aromatic ketone. It serves as a valuable building block in organic synthesis. Its chemical structure makes it useful for introducing a fluorophenyl group into more complex molecules, particularly in the development of pharmaceuticals and agrochemicals. Available in 98% purity, it is supplied by Tech Serve Solutions for research and development purposes.
Organic Synthesis Intermediate
4′-Fluoropropiophenone is utilised as a precursor in the synthesis of various organic compounds. Its reactive carbonyl group and fluorinated phenyl ring allow for diverse chemical transformations.
Pharmaceutical Building Block
This compound serves as a key intermediate in the development of potential pharmaceutical agents. The presence of fluorine can modulate pharmacokinetic properties like metabolic stability and lipophilicity.
Research and Development
Utilised in academic and industrial laboratories for exploring novel chemical reactions and developing new materials or active pharmaceutical ingredients.
| Molecular weight | 152.17 |
|---|---|
| Linear formula | FC6H4C(O)C2H5 |
| Assay | 98% |
| Density | 1.096 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5059(lit.) |
| Application | 4′-Fluoropropiophenone was used in the preparation of 2-(4-fluorophenyl)-3-methylquinoxaline1. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 77 °C / 170.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Fluoropropiophenone used for?
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4′-Fluoropropiophenone is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates and other complex organic molecules.
What is the CAS number and molecular formula for 4′-Fluoropropiophenone?
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The CAS number for 4′-Fluoropropiophenone is 456-03-1, and its molecular formula is FC<sub>6</sub>H<sub>4</sub>C(O)C<sub>2</sub>H<sub>5</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Fluoropropiophenone with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4′-Fluoropropiophenone be handled safely?
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4′-Fluoropropiophenone is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, face shields, and gloves, should be worn. Use in a well-ventilated area and consult the Safety Data Sheet for detailed handling procedures.
Is 4′-Fluoropropiophenone shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4′-Fluoropropiophenone.
How can I request a quote or sample for 4′-Fluoropropiophenone?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (456-03-1).
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