4′-Fluoroacetophenone
4′-Fluoroacetophenone (CAS: 403-42-9) is a fluorinated aromatic ketone with the molecular formula C<sub>8</sub>H<sub>7</sub>FO and a molecular weight of 138.14 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for introducing a fluorinated acetophenone moiety into larger molecules. Its reactivity makes it useful in the development of new pharmaceuticals and agrochemicals. Tech Serve Solutions supplies this chemical with an assay of 99%.
- Synonyms
- 4-Fluoroacetophenonep-Fluoroacetophenone1-(4-Fluorophenyl)ethanone
Pharmaceutical Intermediate
4′-Fluoroacetophenone is utilised in the synthesis of active pharmaceutical ingredients (APIs). Its structure allows for further chemical modifications essential for drug discovery and development.
Agrochemical Synthesis
This compound acts as a key intermediate in the creation of novel agrochemicals. The presence of fluorine can impart desirable properties such as enhanced efficacy and metabolic stability.
Research and Development
As a versatile organic building block, 4′-Fluoroacetophenone is employed in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities.
Material Science
Fluorinated organic compounds often find applications in material science due to their unique electronic and physical properties. 4′-Fluoroacetophenone can be a precursor for specialised materials.
| Molecular weight | 138.14 |
|---|---|
| Linear formula | FC6H4COCH3 |
| Assay | 99% |
| Boiling point | 196 °C(lit.) |
| Density | 1.138 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.511(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Fluoroacetophenone used for?
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4′-Fluoroacetophenone is primarily used as an intermediate in pharmaceutical and agrochemical synthesis, and in general organic chemical research and development.
What is the CAS number and chemical formula for 4′-Fluoroacetophenone?
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The CAS number is 403-42-9 and the linear formula is FC₆H₄COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Fluoroacetophenone with a minimum assay of 99%. This is a technical grade for research and synthesis; it is not represented as USP, BP, EP or other pharmacopoeia grades.
What are the safety and handling precautions for 4′-Fluoroacetophenone?
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4′-Fluoroacetophenone is a warning-level irritant (H315, H319, H335). Handle with appropriate personal protective equipment including safety glasses, chemical-resistant gloves, and use in a well-ventilated area or fume hood. Avoid breathing vapours or dust.
How is 4′-Fluoroacetophenone packed, shipped, and exported?
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Tech Serve Solutions packs and ships chemicals according to international regulations, ensuring safe transport. As a global supplier, we handle export documentation and logistics for international customers.
How can I request a sample or quote for 4′-Fluoroacetophenone?
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To request a sample or a quote, please contact our sales department through the website or via email, specifying the product name and CAS number (403-42-9).
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