4-Fluorobenzenesulfonamide
4-Fluorobenzenesulfonamide (CAS: 402-46-0), with the molecular formula FC6H4SO2NH2 and a molecular weight of 175.18 g/mol, is a key fluorinated organic building block. This compound serves as a valuable intermediate in various chemical synthesis pathways, particularly in the development of pharmaceuticals and agrochemicals. Its structure allows for diverse chemical transformations, making it a sought-after reagent for researchers and industrial chemists.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), leveraging its fluorinated aryl sulfonamide structure for drug discovery and development.
Agrochemical Synthesis
A building block for the creation of novel pesticides, herbicides, and fungicides, contributing to advancements in crop protection.
Organic Synthesis Reagent
Employed as a versatile reagent in general organic synthesis, enabling the introduction of the 4-fluorobenzenesulfonyl group into various molecules.
Material Science Research
Investigated for potential applications in the development of new materials due to its unique chemical properties derived from the fluorine and sulfonamide moieties.
| Molecular weight | 175.18 |
|---|---|
| Linear formula | FC6H4SO2NH2 |
| Assay | 98% |
| Melting point | 124-127 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorobenzenesulfonamide used for?
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4-Fluorobenzenesulfonamide (CAS: 402-46-0) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also employed in material science research.
What are the CAS number and formula for 4-Fluorobenzenesulfonamide?
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The CAS number for 4-Fluorobenzenesulfonamide is 402-46-0, and its linear formula is FC6H4SO2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorobenzenesulfonamide with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should 4-Fluorobenzenesulfonamide be handled safely?
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4-Fluorobenzenesulfonamide is a 'Danger' hazard material. Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Avoid inhalation, skin contact, and ingestion. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and respiratory irritation.
Is 4-Fluorobenzenesulfonamide a controlled substance?
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The provided data does not indicate that 4-Fluorobenzenesulfonamide (CAS: 402-46-0) is a controlled substance.
How is 4-Fluorobenzenesulfonamide packed and exported?
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Tech Serve Solutions packages and exports chemicals according to international shipping regulations and customer requirements. Please contact us for specific details regarding packing and export services for 4-Fluorobenzenesulfonamide.
How can I request a quote or sample for 4-Fluorobenzenesulfonamide?
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To request a quote or sample for 4-Fluorobenzenesulfonamide, please contact our sales department via the website or by phone, providing your contact details and the quantity required.
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