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4-Fluoroaniline

CAS 371-40-4FC6H4NH2Chemical Synthesis

4-Fluoroaniline (CAS: 371-40-4), with the molecular formula FC6H4NH2 and a molecular weight of 111.12 g/mol, is a fluorinated aromatic amine. It serves as a crucial building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. This compound is valued for introducing a fluorine atom into molecular structures, influencing their electronic properties and biological activity. Tech Serve Solutions supplies this reagent for research and development purposes.

IUPAC
1-Amino-4-fluorobenzene
Synonyms
1-Amino-4-fluorobenzene4-Aminofluorobenzene
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4-Fluoroaniline (FC6H4NH2) — chemical structure, CAS 371-40-4; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisFluorinated Building BlocksNitrogen CompoundsOrganic Building Blocks
01 /Applications

Pharmaceutical Intermediate

4-Fluoroaniline is employed in the synthesis of various active pharmaceutical ingredients (APIs). Its fluorinated structure can enhance metabolic stability and bioavailability of drug candidates.

Agrochemical Synthesis

This compound acts as a precursor in the production of certain pesticides and herbicides. The fluorine substituent can improve the efficacy and environmental profile of agrochemical products.

Organic Synthesis Building Block

As a versatile fluorinated aryl amine, 4-Fluoroaniline is utilized in a wide range of organic transformations to construct complex molecules for research and material science applications.

02 /Properties
Molecular weight111.12
Linear formulaFC6H4NH2
Assay≥97.0% (GC)
Boiling point187 °C/767 mmHg(lit.)
Density1.173 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.539(lit.)n20/D 1.540
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point74 °C / 165.2 °F
Transport (UN / ADR)UN 2941 6.1 / PGIII
Water hazard class (WGK, DE)1
Hazard codes (EU)C
Risk statements (R)22-34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
371-40-4
MDL number
MFCD00007829
PubChem substance
24894858
Beilstein registry
742030
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Fluoroaniline used for?

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4-Fluoroaniline is primarily used as a building block in organic synthesis, notably in the development of pharmaceuticals and agrochemicals.

What are the CAS number and molecular formula for 4-Fluoroaniline?

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The CAS number for 4-Fluoroaniline is 371-40-4, and its molecular formula is FC6H4NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Fluoroaniline with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.

What are the primary hazards associated with 4-Fluoroaniline?

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4-Fluoroaniline is classified as Dangerous. It causes severe skin burns and eye damage (H314) and is harmful if swallowed (H302). Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, must be used when handling.

How is 4-Fluoroaniline packed and shipped?

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4-Fluoroaniline is packed according to relevant safety regulations for hazardous materials and is exported globally by Tech Serve Solutions.

How can I request a sample or quote for 4-Fluoroaniline?

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To request a sample or quote for 4-Fluoroaniline, please contact the Tech Serve Solutions sales team through our website or designated contact channels.

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