4-Fluoro-α-methylbenzylamine
4-Fluoro-α-methylbenzylamine (CAS: 403-40-7), with the molecular formula FC₆H₄CH(CH₃)NH₂, is a fluorinated organic building block. This amine derivative is primarily utilised in chemical synthesis. It plays a role in nucleophilic substitution reactions and has been employed in the development of compounds with specific biological activities, such as diuretic and saluretic properties.
Synthesis of Bioactive Compounds
4-Fluoro-α-methylbenzylamine has been used in the synthesis of novel thioureas exhibiting diuretic and saluretic activities, demonstrating its utility in pharmaceutical research and development.
Nucleophilic Substitution Reactions
This compound serves as a valuable reagent in organic synthesis for nucleophilic substitution reactions, allowing for the introduction of the 4-fluoro-α-methylbenzylamino moiety into various molecular structures.
Fluorinated Building Block
As a key fluorinated building block, it is employed in the construction of complex organic molecules where the presence of fluorine is desired for its impact on physicochemical and biological properties.
| Molecular weight | 139.17 |
|---|---|
| Linear formula | FC6H4CH(CH3)NH2 |
| Assay | 96% |
| Boiling point | 145 °C(lit.) |
| Density | 1.059 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.502(lit.) |
| Application | 4-Fluoro-α-methylbenzylamine was used in the synthesis of novel thioureas with diuretic and saluretic activity.1 It has also been used for nucleophilic substitution reactions. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 68 °C / 154.4 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-α-methylbenzylamine used for?
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4-Fluoro-α-methylbenzylamine is used in chemical synthesis, particularly in nucleophilic substitution reactions and for the creation of novel compounds with potential pharmaceutical applications, such as diuretic and saluretic agents.
What is the CAS number and molecular formula for 4-Fluoro-α-methylbenzylamine?
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The CAS number for 4-Fluoro-α-methylbenzylamine is 403-40-7, and its molecular formula is FC₆H₄CH(CH₃)NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-α-methylbenzylamine with a minimum assay of 96%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product documentation.
How should 4-Fluoro-α-methylbenzylamine be handled safely?
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4-Fluoro-α-methylbenzylamine is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including gloves, goggles, a face shield, and suitable respiratory protection, must be used. Handle in a well-ventilated area and follow all safety precautions provided in the Safety Data Sheet.
Is 4-Fluoro-α-methylbenzylamine a controlled substance?
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The provided data does not indicate that 4-Fluoro-α-methylbenzylamine (CAS: 403-40-7) is a controlled substance.
How is 4-Fluoro-α-methylbenzylamine packed, shipped, and exported?
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Tech Serve Solutions, a specialist global supplier and exporter since 1998, ensures products like 4-Fluoro-α-methylbenzylamine are packed, shipped, and exported in compliance with relevant regulations.
How can I request a sample or quote for 4-Fluoro-α-methylbenzylamine?
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To request a sample or a quote for 4-Fluoro-α-methylbenzylamine, please contact our sales team through the designated channels on the Tech Serve Solutions website.
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