4-Fluorobenzaldehyde
4-Fluorobenzaldehyde (CAS: 459-57-4; Formula: FC6H4CHO) is a valuable fluorinated aromatic aldehyde with a molecular weight of 124.11 g/mol. This compound serves as a key building block in organic synthesis, particularly in the development of novel pharmaceutical intermediates and advanced materials. Its specific reactivity and the presence of a fluorine atom make it a sought-after reagent for introducing fluorinated moieties into complex molecules.
Pharmaceutical Intermediate Synthesis
4-Fluorobenzaldehyde is utilised in the synthesis of active pharmaceutical ingredients (APIs) and their precursors. For example, it has been employed in the preparation of pyrazolopyridine derivatives, contributing to the development of new therapeutic agents.
Agrochemical Development
The compound finds application in the research and development of novel agrochemicals. Its fluorinated structure can impart unique properties beneficial for pesticide and herbicide design.
Material Science Research
As a versatile building block, 4-Fluorobenzaldehyde is employed in material science for the synthesis of specialised polymers and functional materials where the incorporation of fluorine offers desired characteristics.
| Molecular weight | 124.11 |
|---|---|
| Linear formula | FC6H4CHO |
| Assay | 98% |
| Boiling point | 181 °C/758 mmHg(lit.) |
| Density | 1.157 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.521(lit.) |
| Application | 4-Fluorobenzaldehyde was used in the preparation of pyrazolopyridine UR-137561. |
| Melting point | −10 °C(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 56 °C / 132.8 °F |
| Transport (UN / ADR) | UN 1989C 3 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorobenzaldehyde used for?
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4-Fluorobenzaldehyde is primarily used as a building block in organic synthesis for pharmaceuticals, agrochemicals, and materials science. It has been specifically noted for its use in the preparation of pyrazolopyridine UR-13756.
What are the CAS number and formula for 4-Fluorobenzaldehyde?
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The CAS number for 4-Fluorobenzaldehyde is 459-57-4, and its linear formula is FC6H4CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorobenzaldehyde with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 4-Fluorobenzaldehyde be handled safely?
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4-Fluorobenzaldehyde is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling information.
Is 4-Fluorobenzaldehyde a controlled substance?
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Based on the provided data, 4-Fluorobenzaldehyde is not indicated as a controlled substance. However, regulations can vary by jurisdiction.
How is 4-Fluorobenzaldehyde packed and shipped?
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4-Fluorobenzaldehyde is classified as UN 1989, Class 3, Packing Group III. It is packed and shipped in compliance with relevant transportation regulations for hazardous materials.
How can I request a quote or sample of 4-Fluorobenzaldehyde?
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To request a quote or sample of 4-Fluorobenzaldehyde, please contact our sales department via the website or your dedicated account manager.
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