4-Fluorobenzenesulfonyl chloride
4-Fluorobenzenesulfonyl chloride (CAS: 349-88-2), with the molecular formula FC6H4SO2Cl and a molecular weight of 194.61 g/mol, is a valuable fluorinated aromatic building block. This sulfonyl chloride derivative is primarily utilised in organic synthesis for introducing the 4-fluorobenzenesulfonyl group into various molecules. It serves as a key intermediate in the development of pharmaceuticals, agrochemicals, and specialty materials requiring specific fluorinated functionalities.
Synthesis of Pharmaceuticals
4-Fluorobenzenesulfonyl chloride acts as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its incorporation can modify the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
This compound is employed in the creation of novel agrochemicals, such as herbicides and pesticides. The fluorine atom can enhance the efficacy and stability of these agricultural products.
Material Science
It finds application in the synthesis of functional materials and polymers. The unique properties conferred by the fluorinated phenylsulfonyl moiety can be exploited in advanced material design.
Organic Synthesis Reagent
As a versatile building block, 4-Fluorobenzenesulfonyl chloride is widely used in various organic transformations to construct complex molecular architectures.
| Molecular weight | 194.61 |
|---|---|
| Linear formula | FC6H4SO2Cl |
| Assay | 98% |
| Boiling point | 95-96 °C/2 mmHg(lit.) |
| Melting point | 29-31 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorobenzenesulfonyl chloride used for?
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4-Fluorobenzenesulfonyl chloride is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and specialty materials requiring fluorinated moieties.
What is the CAS number and chemical formula for 4-Fluorobenzenesulfonyl chloride?
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The CAS number is 349-88-2 and the chemical formula is FC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorobenzenesulfonyl chloride with an assay of 98%. This product is supplied for research and technical purposes and is not represented as USP, BP, or EP grade.
How should 4-Fluorobenzenesulfonyl chloride be handled safely?
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This compound is classified as corrosive and can cause severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is 4-Fluorobenzenesulfonyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Fluorobenzenesulfonyl chloride, complying with international shipping regulations (UN 3261, Class 8, Packing Group II).
How can I request a sample or quote for 4-Fluorobenzenesulfonyl chloride?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for 4-Fluorobenzenesulfonyl chloride.
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