4-Fluorobenzoic acid
4-Fluorobenzoic acid (CAS: 456-22-4, Formula: C7H5FO2, Molar Mass: 140.11 g/mol) is a vital organic compound. Characterised by a fluorine atom attached to a benzoic acid moiety, this white crystalline solid serves as a key intermediate in various chemical syntheses. It is particularly valuable in the development of pharmaceuticals, agrochemicals, and advanced materials due to the unique properties imparted by the fluorine substituent. Its sublimation purification ensures high quality.
Pharmaceutical Intermediate
4-Fluorobenzoic acid is a fundamental building block in the synthesis of numerous active pharmaceutical ingredients (APIs). The presence of fluorine can enhance metabolic stability, lipophilicity, and binding affinity of drug molecules.
Agrochemical Synthesis
This compound is utilised in the production of pesticides, herbicides, and fungicides. Fluorinated organic molecules often exhibit enhanced biological activity and environmental persistence suitable for agricultural applications.
Material Science
It serves as a precursor for creating novel polymers and advanced materials. The incorporation of fluorinated aromatic rings can modify material properties such as thermal stability and chemical resistance.
Research and Development
4-Fluorobenzoic acid is a standard reagent in organic chemistry research labs for developing new synthetic methodologies and exploring novel fluorinated compounds.
| Molecular weight | 140.11 |
|---|---|
| Linear formula | FC6H4CO2H |
| Assay | 99% |
| Melting point | 182-184 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Purified By | sublimation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorobenzoic acid used for?
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4-Fluorobenzoic acid is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, as well as in general organic chemistry research.
What is the CAS number and chemical formula for 4-Fluorobenzoic acid?
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The CAS number is 456-22-4 and the chemical formula is FC6H4CO2H (C7H5FO2).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorobenzoic acid with a minimum assay of 99%, purified by sublimation. We do not represent this product as USP, BP, or EP grade.
What are the primary hazards associated with 4-Fluorobenzoic acid?
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4-Fluorobenzoic acid is classified as harmful if swallowed (H302) and causes serious eye damage (H318). Appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves should be worn when handling.
How is 4-Fluorobenzoic acid packed and shipped?
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4-Fluorobenzoic acid is carefully packed for shipment to maintain its integrity and comply with international shipping regulations. TSS is a global supplier and exporter.
How can I request a quote or sample for 4-Fluorobenzoic acid?
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To request a quote or sample, please use the contact form on our website or email our sales department, providing your details and the product CAS number (456-22-4).
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