4-Fluorobenzophenone
4-Fluorobenzophenone (CAS: 345-83-5), with the molecular formula FC6H4COC6H5 and a molecular weight of 200.21 g/mol, is a key fluorinated aromatic ketone. It serves as a versatile building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. Its specific reactivity makes it a valuable intermediate for introducing the 4-fluorobenzoyl moiety into complex molecular structures, facilitating targeted chemical transformations and the creation of novel compounds.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its fluorinated structure can impart desirable pharmacokinetic properties, such as increased metabolic stability and lipophilicity.
Agrochemical Synthesis
Serves as a precursor in the development of novel pesticides, herbicides, and fungicides. The incorporation of fluorine can enhance the efficacy and environmental profile of agrochemical products.
Materials Science
Employed in the creation of specialised polymers and advanced materials. Its rigid aromatic structure and the presence of fluorine contribute to unique material properties like thermal stability and chemical resistance.
Research and Development
A fundamental building block for academic and industrial research laboratories exploring new synthetic methodologies and molecular designs. Enables the investigation of novel chemical entities.
| Molecular weight | 200.21 |
|---|---|
| Linear formula | FC6H4COC6H5 |
| Assay | 97% |
| Melting point | 47-49 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorobenzophenone used for?
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4-Fluorobenzophenone is primarily used as an intermediate in organic synthesis for pharmaceuticals, agrochemicals, and materials science. It is also widely employed in research and development for creating new chemical entities.
What is the CAS number and chemical formula for 4-Fluorobenzophenone?
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The CAS number for 4-Fluorobenzophenone is 345-83-5, and its chemical formula is FC6H4COC6H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluorobenzophenone with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Fluorobenzophenone be handled safely?
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4-Fluorobenzophenone is classified as an irritant. Handle with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling information.
Is 4-Fluorobenzophenone exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Fluorobenzophenone.
How can I request a quote or sample for 4-Fluorobenzophenone?
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To request a quote or sample, please contact our sales team via the website or provide your requirements through our online inquiry form.
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