4-Fluoro-N-methylaniline
4-Fluoro-N-methylaniline (CAS: 459-59-6), with the molecular formula FC₆H₄NHCH₃ and a molecular weight of 125.14 g/mol, is a fluorinated aromatic amine. This compound serves as a valuable building block in organic synthesis. It has been employed as a model compound in studies investigating the biotransformation of secondary aromatic amines, both in vitro and in vivo. Tech Serve Solutions offers this chemical with an assay of 97%.
Biotransformation Studies
4-Fluoro-N-methylaniline has been utilised as a model compound to investigate the in vivo and in vitro biotransformation pathways of secondary aromatic amines. This research aids in understanding metabolic processes and potential toxicological profiles.
Organic Synthesis Intermediate
As an aryl fluorinated building block, it is instrumental in the synthesis of more complex organic molecules. Its structure makes it suitable for introducing a fluorinated N-methylaniline moiety into target compounds.
Research and Development
This compound is valuable for researchers in medicinal chemistry and material science exploring novel compounds with specific electronic or biological properties conferred by the fluorine atom and the N-methylaniline structure.
| Molecular weight | 125.14 |
|---|---|
| Linear formula | FC6H4NHCH3 |
| Assay | 97% |
| Boiling point | 79 °C/11 mmHg(lit.) |
| Density | 1.040 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5320(lit.) |
| Application | 4-Fluoro-N-methylaniline was used as a model compound to study the in vivo and in vitro biotransformation of secondary aromatic amines1. |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 76 °C / 168.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41-43-52/53 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-N-methylaniline used for?
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4-Fluoro-N-methylaniline is used as a model compound for studying the biotransformation of secondary aromatic amines and as a building block in organic synthesis.
What are the CAS number and formula for 4-Fluoro-N-methylaniline?
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The CAS number is 459-59-6, and the linear formula is FC₆H₄NHCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-N-methylaniline with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Fluoro-N-methylaniline be handled safely?
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4-Fluoro-N-methylaniline is a Danger substance. It is harmful if swallowed, causes skin irritation, may cause an allergic skin reaction, causes serious eye damage, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area.
Is 4-Fluoro-N-methylaniline a controlled substance?
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The provided data does not indicate that 4-Fluoro-N-methylaniline is a scheduled or controlled substance.
How is 4-Fluoro-N-methylaniline shipped and exported?
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4-Fluoro-N-methylaniline is classified under UN 2810, 6.1, Packing Group III. Tech Serve Solutions, as an experienced global supplier, adheres to all regulations for the safe packing, shipping, and export of this chemical.
How can I request a quote or sample for 4-Fluoro-N-methylaniline?
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Please contact our sales team or use the online inquiry form on our website to request a quote or sample for 4-Fluoro-N-methylaniline.
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