4-Fluoro-L-phenylalanine hydrochloride
4-Fluoro-L-phenylalanine hydrochloride (CAS: 64231-54-5), with the molecular formula FC6H4CH2CH(NH2)CO2H · HCl and a molecular weight of 219.64 g/mol, is an unnatural amino acid derivative. This compound finds utility in chemical biology and synthesis, particularly within peptide chemistry. Its structure incorporates a fluorine atom on the phenyl ring, offering unique properties for research and development applications.

Chemical Biology Research
Utilised as a building block in chemical biology to synthesise novel compounds and probes. Its fluorine substitution allows for unique spectroscopic analysis and metabolic studies.
Peptide Synthesis
Incorporated into peptides to modify their structure and biological activity. This unnatural amino acid can enhance stability or alter receptor binding profiles.
Drug Discovery and Development
Serves as a valuable intermediate in the synthesis of potential pharmaceutical agents. The fluorinated phenylalanine analogue can be used to explore structure-activity relationships.
Unnatural Amino Acid Studies
Employed in research focused on understanding the role and incorporation of unnatural amino acids into biological systems. Its specific properties aid in studying protein synthesis and function.
| Molecular weight | 219.64 |
|---|---|
| Linear formula | FC6H4CH2CH(NH2)CO2H · HCl |
| Assay | 97% |
| Optical activity | [α]24/D −8°, c = 1 in H2O |
| Melting point | 245-251 °C (dec.)(lit.) |


Hazard statements
- H301Toxic if swallowed
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-L-phenylalanine hydrochloride used for?
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4-Fluoro-L-phenylalanine hydrochloride is used in chemical biology, chemical synthesis, peptide chemistry, and as an unnatural amino acid derivative for research and drug discovery applications.
What is the CAS number and molecular formula?
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The CAS number is 64231-54-5 and the molecular formula is FC6H4CH2CH(NH2)CO2H · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-L-phenylalanine hydrochloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Fluoro-L-phenylalanine hydrochloride be handled?
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This compound is classified as Toxic and may cause genetic defects. Handle with extreme caution, using a dust mask type N95 (US), eyeshields, and gloves. Store in a well-ventilated area and avoid exposure.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Fluoro-L-phenylalanine hydrochloride.
How can I request a sample or quote?
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To request a sample or quote for 4-Fluoro-L-phenylalanine hydrochloride, please contact our sales team through the website or by phone.
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