4-Fluoro-L-α-phenylglycine
4-Fluoro-L-α-phenylglycine (CAS 19883-57-9), with the molecular formula C8H8FNO2 and a molecular weight of 169.15 g/mol, is a specialised unnatural amino acid derivative. It is primarily utilised in chemical synthesis and peptide chemistry. This compound serves as a valuable building block for introducing fluorinated phenylglycine moieties into peptides and other complex organic molecules, finding applications in chemical biology research.

Chemical Synthesis
Serves as a chiral building block for the synthesis of complex organic molecules and peptidomimetics. Its unique structure allows for the introduction of fluorine into peptide chains.
Peptide Chemistry
Incorporated into peptides to modify their properties, such as stability, lipophilicity, and binding affinity. Used in the creation of unnatural peptides for research purposes.
Chemical Biology
Employed as a tool in chemical biology for developing novel probes and investigating biological pathways. The fluorine atom can serve as a label or influence molecular interactions.
| Molecular weight | 169.15 |
|---|---|
| Empirical formula | C8H8FNO2 |
| Assay | ≥99.0% (NT) |
| Optical activity | [α]20/D +138±2°, c = 1% in 1 M HCl |
| Melting point | ≥300 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-L-α-phenylglycine used for?
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4-Fluoro-L-α-phenylglycine is primarily used in chemical synthesis, peptide chemistry, and chemical biology as a building block for creating modified peptides and complex organic molecules.
What is the CAS number and molecular formula for 4-Fluoro-L-α-phenylglycine?
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The CAS number is 19883-57-9 and the molecular formula is C8H8FNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-L-α-phenylglycine with an assay of ≥99.0% (NT). This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 4-Fluoro-L-α-phenylglycine be handled?
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When handling 4-Fluoro-L-α-phenylglycine, it is recommended to use safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary, in accordance with its WGK Germany 3 classification.
How is 4-Fluoro-L-α-phenylglycine packed, shipped, and exported?
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4-Fluoro-L-α-phenylglycine is carefully packed and available for global export by Tech Serve Solutions, a specialist supplier and exporter of fine chemicals since 1998.
How can I request a sample or quote for 4-Fluoro-L-α-phenylglycine?
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Please contact our sales team directly through our website or by phone to request a sample or obtain a quotation for 4-Fluoro-L-α-phenylglycine.
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