Dicyclohexyl(2,4,6-trimethylphenyl)phosphine
Dicyclohexyl(2,4,6-trimethylphenyl)phosphine (CAS: 870703-48-3) is a phosphine ligand with the molecular formula C21H33P and a molecular weight of 316.46 g/mol. This compound serves as a valuable reagent in synthetic organic chemistry, particularly in catalysis. Its specific structure lends itself to applications in cross-coupling reactions and other metal-catalyzed transformations, facilitating efficient bond formation in complex molecular syntheses.
- Synonyms
- 870703-48-3
Catalysis in Organic Synthesis
This phosphine ligand is employed as a component in catalytic systems for various organic transformations. It can coordinate with transition metals to form active catalysts for reactions such as cross-coupling.
Cross-Coupling Reactions
Dicyclohexyl(2,4,6-trimethylphenyl)phosphine is utilised in palladium-catalyzed cross-coupling reactions, like Suzuki, Heck, or Buchwald-Hartwig aminations, where it can influence reaction rates and selectivity.
Ligand Design for Homogeneous Catalysis
It functions as a bulky phosphine ligand, offering specific steric and electronic properties that can be beneficial for tailoring the activity and selectivity of homogeneous catalysts in complex synthetic pathways.
| Molecular weight | 316.46 |
|---|---|
| Empirical formula | C21H33P |
| Assay | 97% |
| Melting point | 81-85 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dicyclohexyl(2,4,6-trimethylphenyl)phosphine used for?
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Dicyclohexyl(2,4,6-trimethylphenyl)phosphine is primarily used as a ligand in homogeneous catalysis, particularly in palladium-catalyzed cross-coupling reactions and other organic synthesis applications where tailored catalytic activity is required.
What are the CAS number and formula for Dicyclohexyl(2,4,6-trimethylphenyl)phosphine?
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The CAS number for Dicyclohexyl(2,4,6-trimethylphenyl)phosphine is 870703-48-3. Its molecular formula is C21H33P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dicyclohexyl(2,4,6-trimethylphenyl)phosphine with a minimum purity of 97%. This product is supplied for research and development purposes and is not intended for pharmaceutical, veterinary, or human consumption.
What are the safety considerations when handling this compound?
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This compound is classified as a Warning (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is recommended to use a dust mask type N95 (US), wear eyeshields and gloves, and ensure adequate ventilation. Always refer to the Safety Data Sheet (SDS) before handling.
How is this chemical packed and shipped?
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Tech Serve Solutions ensures that all chemicals are securely packed in compliance with international shipping regulations for safe transport globally. Specific packaging details are available upon request.
How can I request a quote or sample for Dicyclohexyl(2,4,6-trimethylphenyl)phosphine?
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To request a quote or a sample, please contact our sales department via the website or email, providing the product name, CAS number, and desired quantity.
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