2-Methylthio-2-imidazoline hydriodide
2-Methylthio-2-imidazoline hydriodide (CAS: 5464-11-9) is a heterocyclic organic compound with the molecular formula C4H8N2S · HI and a molecular weight of 244.10 g/mol. This chemical functions as a valuable building block in organic synthesis. It is primarily utilised as a reactant in the preparation of various complex molecules, including kinase inhibitors and potential therapeutic agents.
- IUPAC
- 2-Methylsulfanyl-4,5-dihydro-1H-imidazole hydrogen iodide
- Synonyms
- 2-Methylsulfanyl-4,5-dihydro-1H-imidazole hydrogen iodide

Synthesis of Kinase Inhibitors
Serves as a key reactant in the synthesis of Aurora and epidermal growth factor receptor kinase inhibitors, contributing to the development of novel therapeutic agents.
Antiviral Drug Development
Utilised in the creation of spiro-piperidine inhibitors designed to combat influenza A virus, highlighting its role in antiviral research.
Metabolic Disorder Research
Employed in the synthesis of galegine analogues investigated for their potential in aiding weight loss in mice, relevant to metabolic disorder studies.
Catalysis in Organic Reactions
Acts as a precursor for guanidinyl pyrrolidines, which function as bifunctional catalysts in enantioselective conjugate addition reactions to cyclic enones.
Development of Carbonic Anhydrase Inhibitors
A reactant in the preparation of carbonic anhydrase inhibitors, compounds explored for various medical applications.
CXCR4 Antagonist Synthesis
Used in the synthesis of small molecule CXCR4 antagonists, which are investigated for their therapeutic potential in various disease areas.
| Molecular weight | 244.10 |
|---|---|
| Empirical formula | C4H8N2S · HI |
| Assay | 99% |
| Application | Reactant for synthesis of: Aurora and epidermal growth factor receptor kinase inhibitors1 Spiro-piperidine inhibitors against influenza A virus2 Galegine analogues for aided weight loss in mice3 Guanidinyl pyrrolidines as bifunctional catalysts for enantioselective conjugate additions to cyclic enones4 Carbonic anhydrase inhibitors5 Small molecule CXCR4 antagonists6 |
| Melting point | 144-146 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methylthio-2-imidazoline hydriodide used for?
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2-Methylthio-2-imidazoline hydriodide is used as a reactant in the synthesis of various compounds, including kinase inhibitors, antiviral agents, carbonic anhydrase inhibitors, and CXCR4 antagonists.
What is the CAS number and formula for 2-Methylthio-2-imidazoline hydriodide?
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The CAS number is 5464-11-9 and the formula is C4H8N2S · HI.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methylthio-2-imidazoline hydriodide at a minimum purity of 99%. We do not represent this product as USP, BP, EP or pharmacopoeia grade.
What are the safety considerations when handling this compound?
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Handling this compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK of 3, indicating a high hazard.
How is this chemical packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packing and adherence to shipping regulations for all its chemical products.
How can I request a sample or quote for 2-Methylthio-2-imidazoline hydriodide?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 2-Methylthio-2-imidazoline hydriodide.
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