4-Fluoro-2-iodotoluene
4-Fluoro-2-iodotoluene (CAS: 13194-67-7) is an organohalogen compound with the formula IC6H3(F)CH3 and a molecular weight of 236.03 g/mol. This fluorinated aryl building block serves as a valuable intermediate in organic synthesis, particularly within the pharmaceutical and agrochemical sectors. Its structure, featuring both fluorine and iodine substituents on a toluene ring, allows for diverse chemical transformations and the construction of complex molecular architectures.
Pharmaceutical Synthesis
4-Fluoro-2-iodotoluene is employed as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its reactive iodine atom facilitates cross-coupling reactions, enabling the introduction of complex functionalities relevant to drug discovery and development.
Agrochemical Development
This compound finds application in the development of novel agrochemicals. The presence of fluorine can influence the biological activity and environmental persistence of resulting pesticides and herbicides.
Organic Building Block
As a versatile building block, 4-Fluoro-2-iodotoluene is utilized in general organic synthesis for creating bespoke molecules. It is particularly useful for introducing fluorinated aryl moieties into target compounds.
Materials Science
The unique electronic properties conferred by the fluorine and iodine atoms make this compound a potential precursor in the synthesis of advanced materials, such as organic semiconductors or liquid crystals.
| Molecular weight | 236.03 |
|---|---|
| Linear formula | IC6H3(F)CH3 |
| Assay | 97% |
| Boiling point | 92-94 °C/15 mmHg(lit.) |
| Density | 1.752 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5800(lit.) |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-52/53 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-iodotoluene used for?
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4-Fluoro-2-iodotoluene is used as an intermediate in pharmaceutical synthesis, agrochemical development, and general organic synthesis for creating bespoke molecules. It is particularly useful for introducing fluorinated aryl moieties into target compounds.
What is the CAS number and chemical formula for 4-Fluoro-2-iodotoluene?
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The CAS number for 4-Fluoro-2-iodotoluene is 13194-67-7 and its chemical formula is IC6H3(F)CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-2-iodotoluene with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for 4-Fluoro-2-iodotoluene?
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4-Fluoro-2-iodotoluene is classified as Danger (GHS06) and is toxic if swallowed (H301). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, appropriate gloves, and a suitable respirator. Always consult the Safety Data Sheet (SDS) before use.
How is 4-Fluoro-2-iodotoluene packed, shipped, and exported?
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Tech Serve Solutions expertly packs, handles, and exports chemicals globally, adhering to all relevant transportation and regulatory guidelines for hazardous materials like UN 2810.
How can I request a sample or quote for 4-Fluoro-2-iodotoluene?
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To request a sample or quote for 4-Fluoro-2-iodotoluene, please contact our sales team through the website or your dedicated account manager.
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