4-Fluoro-2-(trifluoromethyl)phenylacetonitrile
4-Fluoro-2-(trifluoromethyl)phenylacetonitrile (CAS 80141-94-2) is an organofluorine compound with the chemical formula FC6H3(CF3)CH2CN and a molecular weight of 203.14 g/mol. This nitrile, featuring both fluorine and trifluoromethyl substituents on an aromatic ring, serves as a valuable intermediate in organic synthesis. It is particularly useful in the construction of complex molecules for research and development purposes, contributing to advancements in various chemical fields.
Pharmaceutical Intermediate
Used as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its fluorinated structure can impart desirable pharmacokinetic properties.
Agrochemical Synthesis
Serves as a precursor in the development of novel agrochemicals, including pesticides and herbicides. The trifluoromethyl group is common in modern crop protection agents.
Materials Science Research
Employed in the creation of specialty materials where fluorination is beneficial for properties such as thermal stability or chemical resistance.
Organic Synthesis Reagent
A versatile reagent for introducing the 4-fluoro-2-(trifluoromethyl)phenylacetonitrile moiety into larger molecular structures during multi-step chemical processes.
| Molecular weight | 203.14 |
|---|---|
| Linear formula | FC6H3(CF3)CH2CN |
| Assay | 97% |
| Boiling point | 222-223 °C(lit.) |
| Density | 1.364 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.451(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-(trifluoromethyl)phenylacetonitrile used for?
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4-Fluoro-2-(trifluoromethyl)phenylacetonitrile is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. Its structure makes it a valuable building block for introducing fluorinated aromatic groups.
What are the CAS number and chemical formula for 4-Fluoro-2-(trifluoromethyl)phenylacetonitrile?
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The CAS number is 80141-94-2, and the chemical formula is FC6H3(CF3)CH2CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-2-(trifluoromethyl)phenylacetonitrile with an assay of 97%. This is a technical grade suitable for research and synthesis; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound requires careful handling. Personal protective equipment, including eyeshields, gloves, and appropriate respiratory protection (half-mask respirator EU/US, or multi-purpose combination cartridge US), is essential. It has a flash point of 107 °C (224.6 °F) and is classified under WGK Germany as 3, indicating a high hazard to water.
How is this product packed, shipped, and exported?
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Tech Serve Solutions ensures secure and compliant packaging for all its chemical products. We export globally, adhering to all relevant international shipping regulations for hazardous materials.
How can I request a quote or sample for 4-Fluoro-2-(trifluoromethyl)phenylacetonitrile?
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To request a quote or a sample, please contact our sales department directly through the website or by phone. Our team will be happy to assist you with your inquiry.
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