4-Fluoro-2-(trifluoromethyl)benzoyl chloride
4-Fluoro-2-(trifluoromethyl)benzoyl chloride (CAS 189807-21-4) is an organic compound with the molecular formula C8H3ClF4O. This fluorinated acid halide serves as a valuable intermediate in organic synthesis. It is primarily utilized as a building block for introducing the 4-fluoro-2-(trifluoromethyl)benzoyl moiety into more complex molecules, finding application in the development of pharmaceuticals and agrochemicals.
Pharmaceutical Intermediate
This compound is employed in the synthesis of active pharmaceutical ingredients (APIs). Its specific structure allows for the introduction of fluorine and trifluoromethyl groups, which can enhance drug efficacy and metabolic stability.
Agrochemical Synthesis
It acts as a key building block in the production of various agrochemicals. The incorporation of fluorinated motifs often contributes to improved biological activity and persistence in crop protection agents.
Organic Synthesis Reagent
As an acid chloride, it readily reacts with nucleophiles such as alcohols, amines, and phenols. This reactivity makes it a versatile reagent for acylation reactions in complex organic synthesis pathways.
| Molecular weight | 226.56 |
|---|---|
| Linear formula | FC6H3(CF3)COCl |
| Assay | 97% |
| Boiling point | 157 °C(lit.) |
| Density | 1.495 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.468(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-(trifluoromethyl)benzoyl chloride used for?
+
4-Fluoro-2-(trifluoromethyl)benzoyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals due to its fluorinated structure.
What is the CAS number and molecular formula for 4-Fluoro-2-(trifluoromethyl)benzoyl chloride?
+
The CAS number is 189807-21-4 and the linear molecular formula is FC6H3(CF3)COCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Fluoro-2-(trifluoromethyl)benzoyl chloride with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How is 4-Fluoro-2-(trifluoromethyl)benzoyl chloride supplied and exported?
+
This product is classified under UN 3265, Hazard Class 8, Packing Group II. We adhere to all regulations for its safe handling, packing, and international export as a hazardous material.
What are the safety considerations for handling 4-Fluoro-2-(trifluoromethyl)benzoyl chloride?
+
This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, gloves, goggles, and suitable respiratory protection, must be used. Handle in a well-ventilated area.
How can I request a quote or sample for 4-Fluoro-2-(trifluoromethyl)benzoyl chloride?
+
Please contact our sales team through the website or by phone to request a quotation or to arrange for a product sample.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis