4-Fluoro-2-(trifluoromethyl)aniline
4-Fluoro-2-(trifluoromethyl)aniline (CAS: 393-39-5) is an organic compound with the formula FC<sub>6</sub>H<sub>3</sub>(CF<sub>3</sub>)NH<sub>2</sub>. Its molecular weight is 179.11 g/mol. This fluorinated aromatic amine serves as a key building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique structure, featuring both fluorine and a trifluoromethyl group, makes it valuable for introducing specific properties into target molecules.
- IUPAC
- 2-Amino-5-fluorobenzotrifluoride,α,α,α,4-Tetrafluoro-o-toluidine
- Synonyms
- 2-Amino-5-fluorobenzotrifluorideα,α,α,4-Tetrafluoro-o-toluidine
Pharmaceutical Intermediate
Used as a precursor in the synthesis of complex organic molecules, potentially for pharmaceutical applications. The presence of fluorine and trifluoromethyl groups can influence the pharmacokinetic properties of drug candidates.
Agrochemical Synthesis
Serves as a building block for the creation of novel agrochemicals. Fluorinated compounds are often employed in pesticides and herbicides due to their enhanced stability and biological activity.
Organic Synthesis Reagent
A versatile reagent in general organic synthesis, enabling the introduction of the 4-fluoro-2-(trifluoromethyl)phenyl moiety into various molecular structures.
| Molecular weight | 179.11 |
|---|---|
| Linear formula | FC6H3(CF3)NH2 |
| Assay | 99% |
| Boiling point | 70-72 °C/17.5 mmHg(lit.) |
| Density | 1.38 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.464(lit.) |
| Storage temperature | 2-8°C |
| Application | 4-Fluoro-2-(trifluoromethyl)aniline was used in the preparation of 2-[4-(3-bromophenyl)-7-chloro-6-methyl-2-oxo-2H-chromen-3-yl]-N-[4-fluoro-2-(trifluoro-methyl)phenyl]acetamide1. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-(trifluoromethyl)aniline used for?
+
4-Fluoro-2-(trifluoromethyl)aniline is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also utilized as a reagent in general chemical synthesis.
What are the CAS number and formula for 4-Fluoro-2-(trifluoromethyl)aniline?
+
The CAS number is 393-39-5 and the linear formula is FC<sub>6</sub>H<sub>3</sub>(CF<sub>3</sub>)NH<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Fluoro-2-(trifluoromethyl)aniline with an assay of 99%. This product is supplied for research and development purposes and is not represented as USP, BP, or EP grade.
What are the safety considerations for handling 4-Fluoro-2-(trifluoromethyl)aniline?
+
This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation (H302, H312, H332, H315, H319, H335). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
How is 4-Fluoro-2-(trifluoromethyl)aniline packed, shipped, and exported?
+
Tech Serve Solutions expertly packs and ships chemicals globally, adhering to all relevant international regulations for safe transport. Please contact us for specific shipping and export details.
How can I request a sample or quote for 4-Fluoro-2-(trifluoromethyl)aniline?
+
To request a sample or a quote, please use the 'Request a Quote' or 'Sample Request' feature on our website, or contact our sales team directly with your inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis